Faculty of Health Sciences: Recent submissions
Now showing items 841-860 of 2404
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MAO inhibitors and their wider applications: a patent review
(Taylor & Francis, 2018)Introduction: Monoamine oxidase (MAO) inhibitors, after the initial ‘golden age’, are currently used as third-line antidepressants (selective MAO-A inhibitors) or clinically enrolled as co-adjuvants for neurodegenerative ... -
Team-based learning experiences of fourth-year pharmacy students in a South African university
(AACP, 2018)Objective. To determine fourth-year pharmacy students’ learning experiences with team-based learning (TBL) at a South African university. Methods. A survey composed of biographical data and quantitative questions focusing ... -
Socio-demographic correlates of volunteerism among undergraduate students at North-West University, South Africa
(Taylor & Francis, 2017)This article reports on a study that used a sample of undergraduate students at the North-West University, Mafikeng Campus, South Africa, to examine the effect of selected sociodemographic factors on ... -
The psychology of forgiveness and its importance in South Africa
(Sage, 2017)The purpose of this qualitative review is to stimulate empirical research on forgiveness within South Africa (and other portions of Africa). The article explores a Western understanding of the psychology of forgiveness, ... -
Level of agreement between physical activity levels measured by ActiHeart and the International Physical Activity Questionnaire in persons with intellectual disability
(Taylor & Francis, 2018)Purpose: The purpose of this study was to determine the level of agreement between objective physical activity (PA) (ActiHeart®) and subjective proxy-respondent International Physical Activity Questionnaire-short version ... -
Multi-targeted directed ligands for Alzheimer’s disease: design of novel lead coumarin conjugates
(Taylor & Francis, 2018)Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by central nervous system insults with progressive cognitive (memory, attention) and non-cognitive (anxiety, depression) impairments. Pathophysiological ... -
Body image of highly trained female athletes engaged in different types of sport
(Hindawi, 2018)Background.The aim of the study was to evaluate differences in body image across different types of sports in highly trained female athletes. Methods. 242 female individuals, aged 13–30 years (M = 20.0, SD = 4.5), ... -
Validation of the Stress Overload Scale and Stress Overload Scale-short form among a Setswana-speaking community in South Africa
(Sage, 2018)Although there has been extensive research on the phenomenon of stress, there is still a lack of assessment tools, especially in the South African context, that have strong theoretical underpinnings, tapping into both ... -
Inequalities in the use of secondary prevention of cardiovascular disease by socioeconomic status: evidence from the PURE observational study
(Elsevier, 2018)Background There is little evidence on the use of secondary prevention medicines for cardiovascular disease by socioeconomic groups in countries at different levels of economic development. Methods We assessed use of ... -
Inventory on the dietary assessment tools available and needed in Africa: a prerequisite for setting up a common methodological research infrastructure for nutritional surveillance, research, and prevention of diet-related non-communicable diseases
(Taylor & Francis, 2018)Objective: To carry out an inventory on the availability, challenges, and needs of dietary assessment (DA) methods in Africa as a pre-requisite to provide evidence, and set directions (strategies) for implementing common ... -
Assessing mental health services in a rural setting: service providers’ perspective
(Taylor & Francis, 2018)Addressing the inadequate and poor provision of mental health services in rural areas is a world-wide challenge. Most people with mental illness in these areas do not have access to mental health services. Using eight ... -
CRP genotypes predict increased risk to co-present with low vitamin D and elevated CRP in a group of healthy black South African women
(MDPI, 2018)Low 25-hydroxyvitamin D (25(OH)D) and elevated C-reactive protein (CRP) concentrations are independently associated with adverse health outcomes, including cardiovascular disease (CVD). Although an inverse association ... -
Infant development at the age of 6 months in relation to feeding practices, iron status, and growth in a peri-urban community of South Africa
(MDPI, 2018)Background: Evidence on the association between feeding practices, iron deficiency, anaemia, stunting, and impaired psychomotor development during infancy is limited. This study assessed the association between psychomotor ... -
Marinobufagenin is related to elevated central and 24-h systolic blood pressures in young black women: the African-PREDICT study
(Nature, 2018)Marinobufagenin (MBG) is an endogenous steroidal α1-Na+K+-ATPase inhibitor. Because of its role in sodium handling, MBG has been associated with both antihypertensive and prohypertensive effects in normal physiology and ... -
Understanding goal motivations in deprived contexts: perspectives of adults in two rural South African communities
(Springer, 2018)The aim of the present study was to explore and describe the goals and motivations underlying them for adults living in rural African contexts using an inductive approach. Seventy participants (n = 25 males, n = 45 females) ... -
68Ga-NOTA-functionalized ubiquicidin: cytotoxicity, biodistribution, radiation dosimetry, and first-in-human PET/CT imaging of infections
(Society of Nuclear Medicine and Molecular Imaging, 2018)Ubiquicidin is an antimicrobial peptide with great potential for nuclear imaging of infectious diseases, as its cationic-rich fragment TGRAKRRMQYNRR (UBI) has been functionalized with NOTA to allow complexation to 68Ga ... -
Incorporating orange-fleshed sweet potato into the food system as a strategy for improved nutrition: the context of South Africa
(Elsevier, 2018)Orange-fleshed sweet potato (OFSP) is considered the single most successful example of biofortification of a staple crop, and presents a feasible option to address vitamin A deficiency. Though initially promoted as part ... -
Erythropoietin prevents the effect of chronic restraint stress on the number of hippocampal CA3c dendritic terminals-relation to expression of genes involved in synaptic plasticity, angiogenesis, inflammation, and oxidative stress in male rats
(Wiley, 2018)Stress-induced allostatic load affects a variety of biological processes including synaptic plasticity, angiogenesis, oxidative stress, and inflammation in the brain, especially in the hippocampus. Erythropoietin (EPO) is ... -
Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents
(Elsevier, 2018)New 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives are proposed as dual-target-directed monoamine oxidase B (MAO-B) and acetylcholinesterase (AChE) inhibitors, as well as antioxidant agents, for the treatment of ... -
Poly(amidoamine) dendrimers as a pharmaceutical excipient. Are we there yet?
(Elsevier, 2018)Drug solubility could affect the therapeutic use of a drug because the biological activity of a drug is only possible if some fraction of a dissolved drug can permeate and overcome biological membranes to reach its site ...
