Browsing Faculty of Health Sciences by Issue Date

Variable-temperature X-ray powder diffraction analysis of the crystal transformation of the pharmaceutically preferred polymorph C of mebendazole

De Villiers, Melgardt M.; Terblanche, Rudolf J.; Liebenberg, Wilna; Swanepoel, Erna; Dekker, Theo G. (Elsevier, 2005)

Mebendazole is a common benzimidazole anthelmintic that is water insoluble. It is reported to exist in three different polymorphic forms in the solid state, i.e. polymorph A, B and C. Form C is the pharmaceutically preferred ...

Synthesis and transdermal properties of acetylsalicylic acid and selected esters

Gerber, Minja; Breytenbach, Jaco C.; Du Plessis, Jeanetta; Hadgraft, Jonathan (Elsevier, 2006)

The primary aim of this study was to determine the transdermal penetration of acetylsalicylic acid and some of its derivatives, to establish a correlation, if any, with selected physicochemical properties and to determine ...

Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients

Otto, A.; Hadgraft, J.; Du Plessis, J.; Wiechers, J.W.; Kelly, C.L. (Karger, 2008)

In this study the effect of 2 penetration modifiers, dimethyl isosorbide (DMI) and diethylene glycol monoethyl ether (DGME) on the skin delivery of hydroquinone (HQ), salicylic acid (SA) and octadecenedioic acid (DIOIC) ...

Die invloed van fisieke-aktiwiteitsdeelname op die verband tussen die koronêrerisiko-indeks en enkele demografiese konstrukte by NG-predikante in Suid-Afrika

Wilders, Cilas; Strydom, Gert; Kriel, J.S. (University of South Africa, the Department of Practical theology, 2008)

The objective of this study was to determine the interaction of physical activity on the relationship between coronary risk index and years of service, congregation size, co-ministership and congregation type of Dutch ...

Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder

Korff, Schaun; Harvey, Brian H.; Stein, Dan J. (Elsevier, 2008)

Stereotypy is an important manifestation of obsessive compulsive disorder (OCD). OCD involves disturbed serotonin and dopamine pathways, and demonstrates a selective response to serotonin reuptake inhibitors (SRI), with ...

Prevalence of drug-drug interactions of antiretroviral agents in the private health care sector in South Africa

Katende-Kyenda, Norah Lucky; Lubbe, M.S.; Serfontein, J.H.P.; Truter, I. (Health & Medical Publishing Group, 2008)

Objectives. Human immunodefiency virus (HIV) infection can be effectively treated with highly active antiretroviral therapy (HAART), requiring concomitant administration of three to four different agents, often with a ...

Studies on cellular resilience and adaptation following acute and repetitive exposure to ozone in cultured human epithelial (HeLa) cells

Brink, Christiaan B.; Pretorius, Anita; Van Niekerk, Barend P.J.; Oliver, Douglas W.; Venter, Daniel P. (Taylor & Francis, 2008)

Ozone is used to treat several medical conditions, while the underlying mechanisms of action are sometimes poorly understood. In the current study, we exposed cultured human epithelial (HeLa) cells acutely and repeatedly ...

The effect of different intervention programmes on the self-concept and motor proficiency of 7- to 9-year-old children with DCD

Nienaber, Alida; Pienaar, Anita; Peens, Anquanette (Wiley-Blackwell, 2008)