Browsing by Subject "Melanoma"
Now showing items 1-7 of 7
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Anti-melanoma activities of artemisone and prenylated amino-artemisinins in combination with known anticancer drugs
(Frontiers Media, 2020)The most frequently occurring cancers are those of the skin, with melanoma being the leading cause of death due to skin cancer. Breakthroughs in chemotherapy have been achieved in certain cases, though only marginal advances ... -
The antimicrobial peptide nisin Z induces selective toxicity and apoptotic cell death in cultured melanoma cells
(Elsevier, 2018)Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells present ... -
Flow Cytometry as an analytical method of drug–induced apoptosis in 3D bioprinted melanoma cells
(IOP, 2023)Three-dimensional (3D) cell culture systems have gained increasing interest in drug discovery and tissue engineering due to its inherent advantages in providing more physiologically relevant information and more predictive ... -
In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells
(Elsevier, 2015)Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also possesses antitumor activity. In seeking to capitalise on the last property, ... -
An in vitro evaluation of the antibacterial and anticancer properties of the antimicrobial peptide nisin Z
(North-West University (South Africa), Potchefstroom Campus, 2018)The rise in antibiotic resistance and the lack of the development of new antibiotics poses a considerable threat to human health. This is especially of concern in individuals who are immune-compromised (due to immunosuppressive ... -
In vitro skin permeation of artemisone and its nano-vesicular formulations
(Elsevier, 2016)The artemisinin derivative artemisone has antitumor activity. In particular when encapsulated in solid lipid nanoparticles (SLNs) and niosomes, it is active against human melanoma A-375 cells, although such formulations ... -
Review of natural compounds for potential skin cancer treatment
(MDPI, 2014)Most anti-cancer drugs are derived from natural resources such as marine, microbial and botanical sources. Cutaneous malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. Various ...