Percutaneous absorption of selected hydrophilic compounds : an in vitro study on hairless mouse skin

Abstract

INTRODUCTION The objective of this study was initially to - contribute to a current data base in order to obtain a set of data on the ether-water partition coefficients and permeability coefficients of a variety of compounds ranging from very hydrophobic to very hydrophilic in order to assess - the relationship between hydrophobicity and percutaneous absorption; and ...