Fisieke aktiwiteit en enkele lipoproteïenparameters by mans met verhoogde totale cholesterolkonsentrasie

Abstract

Physical activity and some lipoproteien parameters amongst men with an increased concentration of total cholesterol. There is epidemiological and experimental evidence suggesting that physical activity may reduce the mortality rate from coronary heart disease (CHD). A high level of cardiorespiratory fitness can be associated with favourable blood pressure, blood lipid and lipoproteien levels, as well as body measurements. The mechanisms associated with the effect of physical activity on CHD mortality levels are still uncertain. A possible explanation is the effect of physical activity on HDL-cholesterol levels. Research has shown a certain amount of interdependency between HDL-cholesterol and LDL-cholesterol concentrations as well as an increase of HDL-cholesterol concentrations with an increase in physical activity levels. The purpose of this study was to determine the effect of physical activity on some lipoproteien levels amongst men with an increased total cholesterol concentration. The independent effects of smoking and obesity, which are normally assosiated with coronary heart disease, was also investigated. Participation in physical activity showed statistically significant (p~0.05) relations with HDL-cholesterol, LDL/HDL-ratio as well as the TC/HDL-ratio. Highly physically active individuals showed a practically significantly (ES~0.5) higher HDL-cholesterol concentration as well as a lower LDL/HDL-ratio and TC/HDL-ratio than physically inactive respondents. Regarding the effect of the covariables (smoking and obesity) on the relationship

between the PAI and the dependent variables it was found that physically active smokers and obese respondents had more favourable LDL/HDL-ratio, TC/HDLratio and HDL-C values than inactive smokers and obese respondents. The physically active smokers and obese respondents also showed similar or more favourable values (HDL-C, LDL/HDL-ratio and TC/HDL-ratio) than inactive non-smokers and non-obese respondents. Two conclusions can thus be drawn from these results. Firstly, it would seem that physical activity can neutralize smoking and obesity's effects on HDL-C, LDL/HDL-ratio and the TC/HDLratio. Secondly, the results suggest that physical activity could lower the CHD risk of respondents with an elevated TC, independent of smoking or obesity.