| dc.contributor.author | Popplewell, Wendy L. | |
| dc.contributor.author | Brand, Linda | |
| dc.contributor.author | Harvey, Brian Herbert | |
| dc.contributor.author | Marais, Eloise A. | |
| dc.contributor.author | Davies-Coleman, Michael T. | |
| dc.date.accessioned | 2012-02-29T09:49:47Z | |
| dc.date.available | 2012-02-29T09:49:47Z | |
| dc.date.issued | 2010 | en_US |
| dc.identifier.citation | Popplewell, W.L. et al. 2010. Euphorbias of South Africa: two new phorbol esters from Euphorbia bothae. South African journal of chemistry. Suid-Afrikaanse tydskrif vir chemie, 63:175-179. [http://hdl.handle.net/10520/EJC24500] | en_US |
| dc.identifier.issn | 0379-4350 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10394/5972 | |
| dc.identifier.uri | http://hdl.handle.net/10520/EJC24500 | |
| dc.identifier.uri | http://journals.co.za/content/chem/63/1/EJC24500 | |
| dc.description.abstract | Two known phorbol esters, 12-deoxyphorbol-13-isobutyrate-20-acetate (1) and 12-deoxyphorbol-13-(2-methylbutyrate)-20-acetate (2), and two new phorbol esters, 12-deoxyphorbol-13-isobutyrate-16-angelate-20-acetate (3) and 12-deoxyphorbol-13-(2-methylbutyrate)-16-angelate-20-acetate (4), were isolated from the endemic South African plant Euphorbia bothae. Standard spectroscopic techniques were used to elucidate the structures of all four compounds. The interaction of 1-4 with opioid receptors was explored in an attempt to explain the unexplained stupor occasionally observed in herbivores browsing on E. bothae | |
| dc.publisher | South African Bureau for Scientific Publications | en_US |
| dc.subject | Euphorbia bothae | |
| dc.subject | Euphorbiaceae | |
| dc.subject | Opioid receptor | |
| dc.subject | Phorbol ester | |
| dc.title | Euphorbias of South Africa: two new phorbol esters from Euphorbia bothae | en_US |
| dc.contributor.researchID | 11083417 - Harvey, Brian Herbert | |
| dc.contributor.researchID | 10066357 - Brand, Linda | |
