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Insult to injury-potential contribution of coronavirus disease-19 to neuroinflammation and the development of HIV-associated neurocognitive disorders

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Mary Ann Liebert

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Severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 is responsible for a new coronavirus disease known as coronavirus disease-19 (COVID-19). SARS-CoV-2 reports neurotropic properties and may have neurological implications, and this creates another health burden for people living with HIV. As yet, the impact of COVID-19 on (neuro)inflammation and the development of HIV-associated neurocognitive disorders (HAND) is not fully known. Here, we reviewed preliminary evidence that provides clues that COVID-19 may exacerbate inflammatory mechanisms related to the development of HAND

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Williams, M.E. & Fielding, B.C. 2020. Insult to injury-potential contribution of coronavirus disease-19 to neuroinflammation and the development of HIV-associated neurocognitive disorders. AIDS research and human retroviruses, (In press). [https://doi.org/10.1089/aid.2020.0136]

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