| dc.contributor.author | Smuts, Cornelius | en_US |
| dc.contributor.author | Hon, G.M. | |
| dc.contributor.author | Hassan, M.S. | |
| dc.contributor.author | Van Rensburg, S.J. | |
| dc.contributor.author | Abel, S. | |
| dc.contributor.author | Marais, D.W. | |
| dc.contributor.author | Van Jaarsveld, P. | |
| dc.contributor.author | Henning, F. | |
| dc.contributor.author | Erasmus, R.T. | |
| dc.contributor.author | Matsha, T. | |
| dc.date.accessioned | 2010-08-04T15:36:01Z | |
| dc.date.available | 2010-08-04T15:36:01Z | |
| dc.date.issued | 2009 | en_US |
| dc.identifier.citation | Smuts, C. et al. 2009. Erythrocyte membrane fatty acids in patients with multiple sclerosis. Multiple Sclerosis, 15(6):759-62, Jun. [https://doi.org/10.1177/1352458509103321] | en_US |
| dc.identifier.issn | 1352-4585 | |
| dc.identifier.issn | 1477-0970 (Online) | |
| dc.identifier.uri | http://hdl.handle.net/10394/3336 | |
| dc.identifier.uri | https://doi.org/10.1177/1352458509103321 | |
| dc.description.abstract | BACKGROUND:
Reports on fatty acids levels in multiple sclerosis remain inconclusive.
OBJECTIVE:
To determine the erythrocyte membrane fatty acid levels in multiple sclerosis patients and correlate with Kurtzke Expanded Disability Status Scale.
METHODS:
Fatty acid composition of 31 multiple sclerosis and 30 control individuals were measured by gas chromatography.
RESULTS:
The membrane phosphatidylcholine C20:4n - 6 concentration was lower in the multiple sclerosis patients when compared to that of the control group, P = 0.04 and it correlated inversely with the EDSS and FSS.
CONCLUSION:
Decrease in C20:4n - 6 in the erythrocyte membrane could be an indication of depleted plasma stores, and a reflection of disease severity. | |
| dc.publisher | SAGE Publications | |
| dc.title | Erythrocyte membrane fatty acids in patients with multiple sclerosis | en_US |
