Health Sciences
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Exploring the athletic-ideal body image and eating disturbances in a selected South African sample
(North-West University (South-Africa), 2019)The athletic-ideal and associated behaviours have not yet been adequately addressed in current literature. For the past two years researchers focused on the thin-ideal internalization. This researcher explored the extent ... -
Development of lipid matrix tablets containing a double-fixed dose combination of artemether and lumefantrine
(North-West University (South-Africa), 2019)Malaria remains one of the most serious vector-borne and prominent life-threatening diseases in sub-Saharan Africa. Africa has the heaviest malarial disease burden in the world, accounting for 91% of the estimated 445 000 ... -
Usage of central nervous system medication in HIV/AIDS patients: Longitudinal analysis (2005-2015) of prevalence and prescribing pattern changes
(North-West University (South-Africa), 2019)The treatment of HIV/AIDS and coexisting psychiatric disorders is critical to the wellbeing of patients. There is currently a dearth of information on the scope of prescribing of central nervous system (CNS) medication ... -
In vitro biocompatibility of transferosomes, ethosomes and transethosomes
(North-West University (South-Africa), 2019)Lipid nanocarriers (LN) for transdermal drug delivery, have gained more interest in recent years, due to their rapid penetration into the skin. Liposomes were investigated in the past with the goal of transdermal drug ... -
The detection and quantification of biomolecules in biological sample matrices
(North-West University (South-Africa), 2019)In the bodies of living humans and animals, endogenous biomolecules, and in particular the chemical messengers, play an essential role in the maintenance and functionality of physiological processes (Daintith, 2008; Gault ... -
Towards the establishment of practice standards for South African school social work: a mixed-method study with special reference to the Free State Province
(North-West University (South-Africa), 2019)Background: Although school social work has been practised in South Africa since the 1980s, employment levels have, until fairly recently, remained relatively low. A marked increase in new appointments, particularly since ... -
Investigation of potential cardiovascular effects of the Pheroid® delivery system in conscious rats
(North-West University (South-Africa), 2019)Aim: The aim of this study was to evaluate the possible cardiovascular effects of the Pheroid® drug delivery system and to determine the possible central nervous effects of its combination with cannabidiol (CBD) in the ... -
Vascular function, oxidative stress and inflammation in South Africans with an active-and inactive lifestyle: the SABPA study
(North-West University (South-Africa), 2019)Motivation - Cardiovascular disease was responsible for 17.5 million deaths in 2014, which made it the main cause of mortality among non-communicable diseases. Statistics from low- and middleincome countries demonstrated ... -
An ex vivo investigation of the potential drug permeation enhancing effects of selected pepper extracts
(North-West University (South-Africa), 2019)Although the oral route is the most preferred and convenient route of drug administration when considering the patient, certain drugs (e.g. protein and peptide drugs) are mostly administrated by means of injections. This ... -
Evaluation of the in vitro antimicrobial activity of the Pheroid®-entrapped plant extract of Agapanthus africanus against human pathogens
(North-West University (South-Africa), 2019)Antimicrobial resistance is a major concern as existing antimicrobials are becoming less effective due to misuse and overuse (WHO, 2018b). Identifying novel compounds or treatments with a possible antimicrobial activity ... -
The association between fracture risk and bone mineral density in black postmenopausal HIV-positive women on HAART
(North-West University (South-Africa), 2019)Background: Osteoporosis affects millions of people, especially postmenopausal women, worldwide. Osteoporosis and associated fractures are also becomming a concern in the HIV-positive population as a result of higher life ... -
Respiratory exposure to hazardous chemical substances during additive manufacturing using nylon and alumide
(North-West University (South-Africa), 2019)Background: In the additive manufacturing (AM) industry there is very little information available regarding the area emission of and personal exposure to HCSs [particulates, metals and volatile organic compounds (VOCs)] ... -
Persistent behavioural phenotypes in the deer mouse and its response to serotonergic and dopaminergic intervention
(North-West University (South-Africa), 2019)Obsessive compulsive disorder (OCD)1 is a debilitating psychiatric disorder that presents with intrusive thoughts (obsessions) and repetitive ritualistic behaviour (compulsions) as main symptoms. Selective reuptake inhibitors ... -
The development of efavirenz and praziquantel amorphous solid dispersions
(North-West University (South-Africa), 2019)Many active pharmaceutical ingredients (API) that are highly permeable, have low aqueous solubility. Such APIs are classified as Biopharmaceutics classification system (BCS) class II drugs. Efavirenz and praziquantel both ... -
The healthiness of processed foods frequently consumed by children in early childhood development centres in the North West Province
(North-West University (South-Africa), 2019)Introduction: The prevalence of infant, childhood and adolescent obesity is increasing globally. In South Africa, 20.5% of children aged two to five years are overweight or obese and regional and international comparisons ... -
Stability of amorphous forms of roxithromycin when encapsulated in liposomes
(North-West University (South-Africa), 2019)Acne vulgaris is a common chronic inflammatory disease, which affects the pilosebaceous units in the dermal layer of the skin (Krautheim & Gollnick, 2004:398; Williams et al., 2012:361). Several factors are involved during ... -
The prevalence and configuration of nausea in patients receiving intravenous chemotherapy in a private oncology centre in South Africa
(North-West University (South-Africa), 2019)The development of effective antiemetic treatment has contributed to the relieving of chemotherapy-induced vomiting in chemotherapy patients. There is, however, a growing concern that chemotherapy-induced nausea and vomiting ... -
Effects of n-3 polyunsaturated fatty acid and iron deficiency, alone and in combination, during early development on colonic inflammation in rats
(North-West University (South-Africa), 2019)Background: It has been shown that poor nutrition during early development has a causal relationship with adverse pregnancy outcomes, morbidity, mortality and the increased risk of short- and long-term adverse health ... -
A metagenomic microbiome investigation in the deer mouse : a translational approach to obsessive-compulsive disorder
(North-West University (South-Africa), 2019)Obsessive-compulsive disorder (OCD)1 is characterized by persistent, intrusive and often anxiety-provoking thoughts, i.e. obsessions and/or ritualistic behaviors (compulsions) that are expressed in an attempt to reduce the ... -
Older adults' experiences of formal community-based care services in Sebokeng : implications for long-term care management
(North-West University (South-Africa), 2019)South Africa’s older population is faced by far-reaching implications for long-term care. Informal long-term care is increasingly becoming less efficient in providing in their care needs. Families are rendered unable to ...
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