Faculty of Health Sciences: Recent submissions
Now showing items 941-960 of 2404
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Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study
(Elsevier, 2017)Background The relation between dietary nutrients and cardiovascular disease risk markers in many regions worldwide is unknown. In this study, we investigated the effect of dietary nutrients on blood lipids and blood ... -
Iodine status and associations with feeding practices and psychomotor milestone development in six-month-old South African infants
(Wiley, 2017)Iodine is important for normal growth and psychomotor development. While infants below 6 months of age receive iodine from breast milk or fortified infant formula, the introduction of complementary foods poses a serious ... -
Exercise-induced physiological lubrication mechanisms dissipating arthritic joint pain
(Southern African Alliance for Sport Science, Physical Education and Recreation, 2017)Arthritis is a painful inflammatory joint disease that limits the affected joint’s range of motion (ROM), muscle strength and endurance. As a result, cardiorespiratory capacity, physical functioning and quality of life of ... -
Preclinical assessment of a 68Ga-DOTA-functionalized depsipeptide as a radiodiagnostic infection imaging agent
(MDPI, 2017)The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed ... -
Sedentary and physical activity patterns in adults with intellectual disability
(MDPI, 2017)Little is known about the patterns of sedentary time (ST) and physical activity (PA) levels throughout the week among adults and older adults with Intellectual Disability (ID). We analyzed ST and PA patterns of adults and ... -
The role of intra-session exercise sequence in the interference effect: a systematic review with meta-analysis
(Springer, 2018)Background There is a necessity for numerous sports to develop strength and aerobic capacity simultaneously, placing a significant demand upon the practice of effective concurrent training methods. Concurrent training ... -
The psycho-hormonal influence of anaerobic fatigue on semi-professional female soccer players
(Elsevier, 2017)Globally it is assumed that high-intensity activities are the general cause of fatigue experienced during a soccer match. However, little is known about the hormonal and psychological effects of fatigue due to these ... -
Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data
(Elsevier, 2017)Background Hypertension is considered the most important risk factor for cardiovascular diseases, but its control is poor worldwide. We aimed to assess the availability and affordability of blood pressure-lowering medicines, ... -
Relationship between calcium intake and anthropometric indices
(Springer, 2012)An emerging body of literature suggests that dietary calcium may play a role in the regulation of body weight and body fat. Literature has shown inverse relationships between calcium intake and body fat percentage and body ... -
Salt use behaviours of Ghanaians and South Africans: a comparative study of knowledge, attitudes and practices
(MDPI, 2017)Salt consumption is high in Africa and the continent also shares the greatest burden of hypertension. This study examines salt-related knowledge, attitude and self-reported behaviours (KAB) amongst adults from two African ... -
Association between objectively measured physical activity, chronic stress and leukocyte telomere length
(Edizioni Minerva Medica, 2017)BACKGROUND: Physical activity (PA ) attenuates chronic stress and age-related and cardiovascular disease risks, whereby potentially slowing telomere shortening. We aimed to study the association between seven-day objectively ... -
5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions
(Elsevier, 2017)Adenosine A1 and A2A receptors are attracting great interest as drug targets for their role in cognitive and motor deficits, respectively. Antagonism of both these adenosine receptors may offer therapeutic benefits in ... -
Long-term effects of pre-pubertal fluoxetine on behaviour and monoaminergic stress response in stress-sensitive rats
(Cambridge Univ Press, 2017)Although prescription rates of antidepressants for children and adolescents have increased, concerns have been raised regarding effects on neurodevelopment and long-term outcome. Using a genetic animal model of depression, ... -
Creating positive practice environments in a primary health care setting
(Wiley, 2017)Aim The aim of this study was to explore and describe the perceptions of nurse managers, nurses, and a physician in the community health centre with the most positive practice environment in a province of South ... -
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: the SABPA study
(Elsevier, 2017)Background Oestradiol has a protective effect on coronary artery health in women but the effect it has on men, is controversial. A translational approach was followed to assess whether sex hormone levels are associated ... -
Probiotic treatment protects against the pro-depressant-like effect of high-fat diet in Flinders Sensitive Line rats
(Elsevier, 2017)Major depressive disorder (MDD) is highly associated with dysmetabolic conditions, such as obesity and diabetes mellitus type 2, and the gut microbiota may interact with both disease entities. We have previously shown that ... -
Methylene blue and its analogues as antidepressant compounds
(Springer, 2017)Methylene Blue (MB) is considered to have diverse medical applications and is a well-described treatment for methemoglobinemias and ifosfamide-induced encephalopathy. In recent years the focus has shifted to MB as an ... -
Discovery versus implementation research on mental disorders in low- and middle-income countries. Editorial
(Cambridge Univ Press, 2017)The 10/90 research gap refers to the fact that only 10% of the world’s research resources are spent in lowand middle-income countries (LMICs) although 90% of preventable deaths occur in these regions: similar disparities ... -
CYP2B6 haplotype predicts efavirenz plasma concentration in black South African HIV-1-infected children: a longitudinal pediatric pharmacogenomic study
(Mary Ann Liebert, 2017)South Africa has the highest burden of the human immunodeficiency virus (HIV) infection globally. Efavirenz (EFV), a frequently used drug against HIV infection, displays a relationship between drug concentration and ... -
Therapeutic potential of selectively targeting the α2c-adrenoceptor in cognition, depression, and schizophrenia: new developments and future perspective
(Frontiers Media, 2017)α2A- and α2C-adrenoceptors (ARs) are the primary α2-AR subtypes involved in central nervous system (CNS) function. These receptors are implicated in the pathophysiology of psychiatric illness, particularly those associated ...
