Faculty of Health Sciences: Recent submissions
Now showing items 901-920 of 2404
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Relationship between selected metabolic risk factors and waist-to-height ratio among employees in Vhembe District Municipality of Limpopo Province, South Africa
(ANSINET, 2018)Background and Objective: Relationship between metabolic risk factors and waist-to-heigh t (WHtR) in population studies are well known. The aim of the study was to investigate the relationship betwee n selected metabolic ... -
Monitoring physical activity after a cardiovascular event: what is ‘fit’ for purpose?
(Sage, 2018)n the September issue of European Journal of Preventive Cardiology, Lavie and colleagues discussed how physical activity across the lifespan is a cost-effective strategy that must be implemented globally to improve overall ... -
Peromyscus maniculatus bairdii as a naturalistic mammalian model of obsessive-compulsive disorder: current status and future challenges
(Springer, 2018)Obsessive-compulsive disorder (OCD) is a prevalent and debilitating condition, characterized by intrusive thoughts and repetitive behavior. Animal models of OCD arguably have the potential to contribute to our understanding ... -
Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A1 and A2A adenosine receptors
(Wiley, 2018)Antagonists of the adenosine receptors (A1 and A2A) are thought to be beneficial in neurological disorders, such as Alzheimer's and Parkinson's disease. The aim of this study was to explore 2-benzylidene-1-tetralone ... -
Water and the relationship to the crystal structure stability of azithromycin: thermal investigations of solvatomorphism, amorphism and polymorphism
(Springer, 2018)This study investigated the solid-state physical stabilities of azithromycin dihydrate (AZM-DH), thermally prepared anhydrate and hemihydrate modifications. Programmed thermal treatment of AZM-DH in DSC yielded the formation ... -
Activities of 11-azaartemisinin and N-sulfonyl derivatives against Neospora caninum and comparative cytotoxicities
(Wiley, 2017)Neosporosis caused by the apicomplexan parasite Neospora caninum is an economically important disease that induces abortion in dairy and beef cattle. There are no vaccines or drugs available on the market for control or ... -
Activities of 11-azaartemisinin and N-sulfonyl derivatives against asexual and transmissible malaria parasites
(Wiley, 2017)Dihydroartemisinin (DHA), either used in its own right or as the active drug generated in vivo from the other artemisinins in current clinical use—artemether and artesunate—induces quiescence in ring-stage parasites of ... -
Conceptualising a proposed support strategy for sexually abused boys in middle childhood
(Univ Stellenbosch, 2017)Male child sexual abuse in middle childhood has serious effects with the increased risk of development of various mental illnesses and disorders, as well as extreme forms of emotional and behavioural problems. This study ... -
A psycho-social therapeutic group work programme preventing the onset of post-traumatic stress disorder among police officials attached to the specialised units in the South African Police Service
(Univ Stellenbosch, 2017)This article focuses on the development of a psycho-social therapeutic programme (PTP) for police officials attached to the specialised units in the North West province. The objective is to prevent the onset of post-traumatic ... -
Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: independent and IL-6-interactive associations
(PLoS, 2017)Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of ... -
Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat
(Springer, 2018)There is abundant evidence for both disorganized redox balance and cognitive deficits in major depressive disorder (MDD). Garcinia mangostana Linn (GM) has anti-oxidant activity. We studied the antidepressant-like and ... -
N-acetyl cysteine reverses bio-behavioural changes induced by prenatal inflammation, adolescent methamphetamine exposure and combined challenges
(Springer, 2018)Rationale Schizophrenia is associated with prenatal inflammation and/or postnatal stressors such as drug abuse, resulting in immune-redox dysfunction. Antioxidants may offer therapeutic benefits. Objectives The objective ... -
Formulation and evaluation of selected transmucosal dosage forms containing a double fixed-dose of acyclovir and ketoconazole
(Elsevier, 2018)Viral and fungal dermatological manifestations are often the first and only sign of HIV/AIDS. They are cosmetically disfiguring and threaten the quality of life, but can be treated by acyclovir and ketoconazole, correspondingly. ... -
Bariatric surgery to reduce mortality in US adults. A public health perspective from the Analysis of the American National Health and Nutrition Examination Survey linked to the US mortality register
(Springer, 2018)Background Type II obesity represents a major pandemic and public health threat in high-income countries. Type II obesity increases the risk of all-cause and specific-cause mortality, and it is widely acknowledged that ... -
The nature of community health care centre practice environments in a province in South Africa
(Unisa Press, 2016)The practice environment plays an important role in nursing. Currently, limited information seems to exist on the nature of practice environments within the primary health care (PHC) context of the public health care sector ... -
Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter
(Hindawi, 2017)Themajor structural component of a blood clot is ameshwork of fibrin fibers. It has long been thought that the internal structure of fibrin fibers is homogeneous; that is, the protein density and the bond density between ... -
Determinants of pre-lacteal feeding practices in urban and rural Nigeria; a population-based cross-sectional study using the 2013 Nigeria demographic and health survey data
(AJOL, 2017)Background: Prelacteal feeding (PLF) is a barrier to exclusive breast feeding. Objective: To determine factors associated with PLF in rural and urban Nigeria. Methods: We utilized data from the 2013 Nigerian Demographic ... -
A health profile associated with excessive alcohol use independently predicts aortic stiffness over 10 years in black South Africans
(Wolters Kluwer, 2017)Objective: Black populations exhibit higher arterial stiffness than whites and suffer a disproportionate burden of cardiovascular disease. It is therefore important to identify modifiable health behaviours predicting large ... -
Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats
(Elsevier, 2017)The rapid and sustained antidepressant properties of ketamine provide evidence of the importance of the glutamatergic system in the neurobiology of depression. The antidepressant-like effects of ketamine are dependent on ...
