Faculty of Health Sciences: Recent submissions
Now showing items 1301-1320 of 2404
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Dietary strategies to treat hyperhomocysteinaemia based on the biochemistry of homocysteine: a review
(MedPharm Publications (Medical and Pharmaceutical Publications), 2014)Hyperhomocysteinaemia is implicated in various diseases, including cardiovascular disease and cancer. Several conditions influence the concentration of homocysteine (Hcy), including demographic, genetic and ... -
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)Background Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ... -
Nutritional management of a patient at high risk of developing refeeding syndrome
(SA Medical Association/MedPharm publishers, 2015)The following case study was discussed during the fourth-year dietetics evaluation process at North-West University, Potchefstroom Campus. It is a reflection of the opinion of the dietitians, students and lecturers involved, ... -
Fortigenic qualities of psychotherapists in practice
(Taylor & Francis, 2015)This brief report presents preliminary findings on the exploration of strengths (fortigenic) qualities of psychotherapists which can buffer them against compassion fatigue. Participants were seven South African psychologists ... -
Loneliness of older immigrant groups in Canada: effects of ethnic-cultural background
(Springer, 2015)This study aimed to explore the loneliness of several groups of older immigrants in Canada compared to native–born older adults. Data from the Canadian General Social Survey, Cycle 22 (N older adults = 3,692) were used. ... -
Visual uncertainty influences the extent of an especial skill
(Elsevier, 2015)An especial skill in basketball emerges through highly repetitive practice at the 15 ft free throw line. The extent of the role vision plays in the emergence of an especial skill is unknown. We examined the especial skills ... -
Synthesis and in vitro biological evaluation of aminoacridines and artemisinin-acridine hybrids
(Elsevier, 2014)During this study, 9-aminoacridine and artemisinin–acridine hybrid compounds were synthesized and the in vitro for antimalarial activity against both the chloroquine sensitive but also gametocytocidal strain (NF54), and ... -
Development and validation of a LC-MS/MS method for the quantitation of lumefantrine in mouse whole blood and plasma
(Elsevier, 2015)A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed and validated for the quantitation of the antimalarial drug, lumefantrine (LF), in mouse whole blood and plasma. The analyte was extracted ... -
Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone mycotoxins
(Springer, 2017)Mycotoxins are toxic secondary metabolites produced by a range of fungi and are common contaminants of agricultural crops. These toxins are chemically diverse and structurally stable, enabling them to enter the food ... -
(Re)creating community: experiences of older women forcibly relocated during apartheid
(Wiley, 2014)This article explores sense of community with a group of older African women, who were forcibly relocated during apartheid. The situation of a marginalised group, with a history of disconnection from younger generations ... -
Nutrition and economic growth in South Africa: a threshold co–integration approach
(Emerald Group Publishing Ltd, 2015)Purpose – The purpose of this paper is to examine asymmetric co-integration effects between nutrition and economic growth for annual South African data from the period 1961-2013. Design/methodology/approach – The authors ... -
Multifunctional enzyme inhibition for neuroprotection: a focus on MAO, NOS, and AChE inhibitors
(Elsevier, 2015)Neurodegenerative disorders are known to be multifactorial in nature and current research focus has moved from a ‘one-drug-one-target approach’ to that of drugs which are able to act at various relevant biological targets. ... -
Interrelationships between visual–motor integration, visual perception, motor coordination and object control skills of grade 1–learners: NW–child study
(University of Stellenbosch Department of sport science, 2015)The aim of this study was to determine the interrelationship of visual–motor integration, visual perception and motor coordination with object control skills in Grade 1–learners in th e North–West Province of South Africa. ... -
Inhibition of monoamine oxidase by benzoxathiolone analogues
(Elsevier, 2016)Inhibitors of the monoamine oxidase (MAO) enzymes are considered useful therapeutic agents, and are used in the clinic for the treatment of depressive illness and Parkinson’s disease. In addition, MAO inhibitors are also ... -
Kaempferol as selective human MAO‑A inhibitor: analytical detection in Calabrian red wines, biological and molecular modeling studies
(ACS, 2016)The purpose of this work was to determine the kaempferol content in three red wines of Calabria, a southern Italian region with a great number of certified food products. Considering that wine cultivar, climate, and soil ... -
Community-engaged curricula in higher education: the case of a master's programme in play therapy
(2015)This article presents the results from research on community-engaged curricula using feedback from international and South African academics who teach on postgraduate programmes with a community engagement component. It ... -
Evaluation of natural and synthetic 1,4-naphthoquinones as inhibitors of monoamine oxidase
(Wiley, 2016)Previous reports have documented that 1,4-naphtho- quinones act as inhibitors of the monoamine oxidase (MAO) enzymes. In particular, fractionation of the extracts of cured tobacco leafs has led to the charac- terization ... -
Leflunomide, a reversible monoamine oxidase inhibitor
(Bentham Science, 2016)A screening study aimed at identifying inhibitors of the enzyme, monoamine oxidase (MAO), among clinically used drugs have indicated that the antirheumatic drug, leflunomide, is an inhibitor of both MAO isoforms. Leflunomide ... -
Religion and culture
(Karger, 2015)Key Messages "Health professionals (HPs) should be aware, sensitive and respectfully support differences in religion, cultural values and dietary practices of clients and patients." HPs should develop cultural ... -
An evaluation of synthetic indole derivatives as inhibitors of monoamine oxidase
(Elsevier, 2016)In a recent study we have shown that several indole-5,6-dicarbonitrile derivatives are potent inhibitors of human monoamine oxidase (MAO) A and B. To expand on these results and to further determine structure–activity ...
