Browsing by Subject "Metabolites"
Now showing items 1-8 of 8
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The application of metabolomics toward pulmonary tuberculosis research
(Elsevier, 2019)In the quest to identify novel biomarkers for pulmonary tuberculosis (TB), high-throughput systems biology approaches such as metabolomics has become increasingly widespread. Such biomarkers have not only successfully been ... -
Assessing the ability of environmental bacteria to inhibit the growth of Batrachochytrium dendrobatidis
(North-West University (South Africa), 2021)Amphibians have been facing devastating declines through the decades and it wasn’t until 1998 that the once enigmatic declines of amphibians were attributed to Batrachochytrium dendrobatidis. This lethal fungal pathogen ... -
Excretion of polycyclic aromatic hydrocarbon metabolites (OH-PAHs) in cattle urine in Ghana
(Elsevier, 2016)Previous studies of polycyclic aromatic hydrocarbons (PAHs) in particulate matter, soils and livers of wild rats indicated that the city centre of Kumasi, Ghana has been severely polluted with high cancer potency. Cattle ... -
Metabolomics biomarkers for tuberculosis diagnostics: current status and future objectives
(Future Medicine, 2017)Numerous studies have contributed to our current understanding of the complex biology of pulmonary tuberculosis and subsequently provided solutions to its control or eradication. Metabolomics, a newcomer to the Omics ... -
New insights into the survival mechanisms of rifampicin-resistant Mycobacterium tuberculosis
(Oxford Univ Press, 2016)Objectives: Rifampicin is considered the most important antibiotic for treating TB, but unfortunately Mycobacterium tuberculosis is rapidly developing resistance to this drug. Despite the fervent research efforts to date, ... -
New sputum metabolite markers implicating adaptations of the host to Mycobacterium tuberculosis, and vice versa
(Elsevier, 2013)In this study, a metabolomics research approach was used to identify new tuberculosis (TB) markers from sputum, in an attempt to better characterise the disease as well as the metabolic response of the host to Mycobacterium ... -
Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice
(Elsevier, 2020)Neonicotinoids (NNs), a widely used class of systemic pesticides, are regarded as exhibiting selective toxicity in insects. However, NNs are suspected of exerting adverse effects on mammals as well, including humans. To ... -
Sex and site differences in urinary excretion of conjugated pyrene metabolites in the West African Shorthorn cattle
(Japanese Society of Veterinary Science, 2018)Industrialization, economic and population growth rates in Ghana have increased the release of contaminants including polycyclic aromatic hydrocarbons (PAHs) into the environment through which humans and animals are ...
