UV spectrophotometric method for the identification and solubility determination of nevirapine
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An UV spectrophotometric method was developed for the quantitative determination of nevirapine in water, methanol and 0.1 N HCl. It was found that qualitative determination is also possible, due to a peak-shift observed with 0.1 N HCl. The solubility at 37°C, for both the anhydrous and Hemihydrated forms of nevirapine, was determined in each of the three solvents.
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Stieger, N. et al. 2009. UV spectrophotometric method for the identification and solubility determination of nevirapine. Die Pharmazie, 64(10):690-691. [https://doi.org/10.1691/ph.2009.9163]