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Life-Saving but Risky: Antiretroviral Therapy and Rising Diabetes Risk in Rural South Africa

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North-West University

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Antiretroviral therapy (ARVs), especially in the form of combination regimens (cARVs), has been one of the greatest medical achievements of our time. For people living with HIV/AIDS (PLWHIV), these drugs transformed a once fatal illness into a manageable chronic condition, giving hope and extending life expectancy. Yet, this progress comes with a new challenge: an increased risk of type-2 Diabetes Mellitus (DM). This study, conducted in a rural South African district, provides compelling evidence that cARVs are strongly linked to the development of diabetes, underscoring the need for vigilance in long-term HIV care

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Short- story, Faculty of Health Sciences (Nursing)-- North-West University, Mahikeng Campus

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Bam, N.E., 2025. Life-Saving but Risky: Antiretroviral Therapy and Rising Diabetes Risk in Rural South Africa [Storytelling based on: Bam, N.E., Mabunda SA, Ntsaba J, Apalata T, Nomatshila SC, and Chitha W (2020) The association between HIV tri-therapy with the development of Type-2 Diabetes Mellitus in a rural South African District: A case-control study. PLoS ONE 15(12): e0244067. https://doi.org/10.1371/journal.pone.0244067], North-West University, http://hdl.handle.net/10394/43479

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