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Solvent inclusion by the anti-HIV drug nevirapine: X-ray structures and thermal decomposition of representative solvates

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dc.contributor.authorCaira, Mino R.
dc.contributor.authorStieger, Nicole
dc.contributor.authorLiebenberg, Wilna
dc.contributor.authorDe Villiers, Melgardt M.
dc.contributor.authorSamsodien, Halima
dc.contributor.researchID12038156 - Stieger, Nicole
dc.contributor.researchID10196226 - Liebenberg, Wilna
dc.date.accessioned2010-01-21T09:29:12Z
dc.date.available2010-01-21T09:29:12Z
dc.date.issued2008
dc.description.abstractFive crystalline solvates of the anti-HIV drug Nevirapine (N), with compositions N·(ethyl acetate)0.5 (1), N·(dichloromethane)0.5 (2), N·(toluene)0.5 (3), N·(water)0.5 (4), and N·(1,4-dioxane)1.5 (5), were isolated and examined by single-crystal X-ray diffraction to determine the topologies of guest inclusion. These features were reconciled with thermal decomposition data for the solvates recorded in thermogravimetric and differential scanning calorimetric traces
dc.identifier.citationCaira, M.R. et al. 2008. Solvent inclusion by the anti-HIV drug nevirapine: X-ray structures and thermal decomposition of representative solvates. Crystal growth & design, 8(1):17-23. [https://doi.org/10.1021/cg070522r]en
dc.identifier.issn1528-7483 (Online)
dc.identifier.issn1528-7505
dc.identifier.urihttp://hdl.handle.net/10394/2762
dc.identifier.urihttps://pubs.acs.org/doi/abs/10.1021/cg070522r
dc.identifier.urihttps://doi.org/10.1021/cg070522r
dc.language.isoenen
dc.publisherACSen
dc.titleSolvent inclusion by the anti-HIV drug nevirapine: X-ray structures and thermal decomposition of representative solvatesen
dc.typeArticleen

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