NWU Institutional Repository

Chronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortex

Simple item page
dc.contributor.authorElfving, Betina
dc.contributor.authorWegener, Gregers
dc.contributor.authorJakobsen, Jakob Lerche
dc.contributor.authorMadsen, Jens Christian Bredahl
dc.contributor.authorMüller, Heidi Kaastrup
dc.contributor.researchID22353003 - Wegener, Gregers
dc.date.accessioned2016-08-18T09:09:47Z
dc.date.available2016-08-18T09:09:47Z
dc.date.issued2015
dc.description.abstractIn the present study the central and peripheral regulation of VEGF, its cognate receptors, and regulators were examined after acute and chronic restraint stress in rats. After chronic restraint stress (6 h per day for 21 days) the protein levels of VEGF (175 ± 24%) and its receptor VEGFR-2 (169 ± 17%) increased significantly in the prefrontal cortex (A and B). mRNA levels of VEGFR-2 (132 ± 11%) were also significantly increased (D). In the hippocampus no significant changes were observed at the mRNA or protein levels. In serum there was a tendency towards increased VEGF protein expression after both acute and chronic restraint stress (C)en_US
dc.identifier.citationElfving, B. et al. 2015. Chronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortex. Synapse, 69(4):190-194. [https://doi.org/10.1002/syn.21808]en_US
dc.identifier.issn0887-4476
dc.identifier.issn1098-2396 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/18314
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/abs/10.1002/syn.21808
dc.identifier.urihttps://doi.org/10.1002/syn.21808
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectELISAen_US
dc.subjectRaten_US
dc.subjectBrainen_US
dc.subjectBlooden_US
dc.subjectReal-time qPCRen_US
dc.subjectImmunoblottingen_US
dc.titleChronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortexen_US
dc.typeArticleen_US

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.61 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Faculty of Health Sciences