| dc.contributor.author | Lourens, A.C.U. | |
| dc.contributor.author | Van Vuuren, S.F. | |
| dc.contributor.author | Viljoen, A.M. | |
| dc.contributor.author | Davids, H. | |
| dc.contributor.author | Van Heerden, F.R. | |
| dc.date.accessioned | 2013-01-16T09:52:41Z | |
| dc.date.available | 2013-01-16T09:52:41Z | |
| dc.date.issued | 2011 | |
| dc.identifier.citation | Lourens, A.C.U. et al. 2011. Antimicrobial activity and in vitro cytotoxicity of selected South African Helichrysum species. South African journal of botany, 77(1):229-235. [https://doi.org/10.1016/j.sajb.2010.05.006] | en_US |
| dc.identifier.issn | 0254-6299 | |
| dc.identifier.uri | http://hdl.handle.net/10394/7909 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0254629910001535 | |
| dc.identifier.uri | https://doi.org/10.1016/j.sajb.2010.05.006 | |
| dc.description.abstract | The antimicrobial activity of 35 indigenous South African Helichrysum species was determined against six microorganisms. Seven of the 36 chloroform:methanol (1:1) extracts (leaf and stem extracts for all plants and an additional flower extract for H. rugulosum) exhibited minimum inhibitory concentration (MIC) values lower than 0.1 mg/ml against Bacillus cereus and/or Staphylococcus aureus. The in vitro cytotoxicity [against transformed human kidney epithelial (Graham) cells, MCF-7 breast adenocarcinoma and SF-268 glioblastoma cells] of these extracts was also determined at a concentration of 0.1 mg/ml using the sulforhodamine B (SRB) assay. For seven species less than 25% growth was observed for the Graham and MCF-7 cell lines at the test concentration. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.subject | Antimicrobial activity | en_US |
| dc.subject | Asteraceae | en_US |
| dc.subject | Cytotoxicity | en_US |
| dc.subject | Helichrysum | en_US |
| dc.title | Antimicrobial activity and in vitro cytotoxicity of selected South African Helichrysum species | en_US |
| dc.type | Article | en_US |
| dc.contributor.researchID | 10948724 - Lourens, Anna Catharina U. | |
