Browsing Health Sciences by Subject "Tuberculosis"
Now showing items 1-10 of 19
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Characterising tuberculosis and treatment failure thereof using metabolomics
(North-West University, Potchefstroom Campus, 2017., 2017)Tuberculosis (TB), a highly contagious bacterial disease caused by Mycobacterium tuberculosis, is considered the leading cause of death globally from a single bacterial pathogen. The latest reports indicate 10.4 million ... -
Combined first line anti-TB drugs: new insights into stability
(North-West University (South-Africa). Potchefstroom Campus, 2019-05)Tuberculosis (TB) is the most prevalent infectious cause of death globally, affecting approximately one-third of the world’s population (Borgdoff et al., 2002). Mycobacterium tuberculosis (M. tuberculosis) is spread ... -
The development and evaluation of a novel hybrid PLGA nanoparticle-Pheroid® with the potential to improve tuberculosis therapy
(North-West University, Potchefstroom Campus, 2018)The development of drug delivery technologies has the potential to bring both therapeutic and commercial value to future healthcare products. Drug delivery technologies are transport vehicles that help overcome the ... -
Development and validation of a molecular diagnostic for tuberculosis
(North-West University (South Africa) , Potchefstroom Campus, 2016)Background: Tuberculosis is a curable disease that is still responsible for more than 1.4 million deaths annually. In the face of the HIV epidemic the modest gains that have been made in trying to control and eradicate the ... -
Die belewenis van die pasiënt en die verpleegkundige tydens tuberkulose-onderrig
(North-West University (South-Africa), 1995)Although tuberculosis is regarded as a curable disease, it was declared a global emergency by the World Health Organization in 1993. One of the factors with a detrimental effect on the struggle against tuberculosis, ... -
The environmental monitoring and quantification of M. tuberculosis occupational exposure risk in various occupational settings in a platinum mine
(North-West University, 2010)Tuberculosis is a disease that has a detrimental effect on the economic growth of South Africa. The country’s TB mortality rate is amongst the highest in the world, and the worst affected industry is mining. Effective ... -
Exploration of support to nurses working in the tuberculosis programme in the primary health care facilities by management in the Matlosana sub–district
(North-West University, 2012)Tuberculosis is a health threat, globally, in Africa, South Africa as well as in the North West Province. Although a number of positive interventions have been implemented, like the introduction of direct observation ... -
Factors influencing non-adherence to tuberculosis treatment in a sub-district of the North West Province
(North-West University, 2018)BACKGROUND: Tuberculosis (TB) is a worldwide concern that leads the researcher to the identification of a research gap regarding non-adherence. Non-adherence in this study refers to missed doses of treatment among pulmonary ... -
The immune modulatory effects of omega-3 polyunsaturated fatty acids and iron as applied in an animal pulmonary tuberculosis model
(North-West University (South-Africa), 2020)Background: Non-resolving inflammation is characteristic of tuberculosis (TB). This leads to lung tissue damage and anaemia of infection, which is associated with poor clinical outcomes. Iron supplementation may have limited ... -
The impact of PheroidTM technology on the bioavailability and efficacy of anti-tuberculosis drugs in an animal model
(North-West University, 2009)Tuberculosis (TB) is a worldwide pandemic with vast challenges in the fight against the disease. Challenges include the long and tedious treatment regimens and chemotherapy with adverse side effects. One approach in ...
