Browsing Health Sciences by Subject "Sulfadoxine"
Now showing items 1-7 of 7
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The development of sulfadoxine and nevirapine pharmaceutical amorphous solid dispersions
(North-West University (South-Africa), 2019)Solid oral dosage forms are the most convenient and prevalent dosage form in the pharmaceutical industry although an estimated 90% of drugs currently in development can be classified as poorly soluble. These drugs will ... -
The influence of buffer composition on the solubility of baclofen and sulfadoxine
(North-West University (South-Africa), 2022)The drug discovery process has developed immensely during the last couple of decades. The Biopharmaceutical Classification System (BCS) is a drug development tool that is based on correlation of solubility and membrane ... -
International pharmacopoeia monographs : antimalarial dosage forms
(North-West University, 2010)Malaria is a disease affecting millions of people in 109 malarious countries and territories, causing approximately one million deaths annually. In 2004 one of the parasites causing human malaria, Plasmodium falciparum, ... -
Investigation of solubility and permeability of sulfadoxine and pyrimethamine mixtures
(North-West University (South Africa) , Potchefstroom Campus, 2017)Sulfadoxine and pyrimethamine are commercially available in a fixed dose combination (FDC) product, which is used as prophylaxis against malaria. These drugs are still on the World Health Organization’s (WHO) essential ... -
The physico-chemical properties and recrystallisation kinetics of selected amorphous active ingredients
(North-West University (South Africa) , Potchefstroom Campus, 2015)During the last two to three decades the application of amorphous solid-state forms within the pharmaceutical industry gained much interest. The rationale for this heightened interest is the increased aqueous solubility, ... -
Solubility and dissolution testing of selected sulfadoxine/pyrimethamine mixtures
(North-West University (South Africa) , Potchefstroom Campus, 2016)Although malaria is an age old disease it continues to plague mankind especially in the African regions. Pregnant women are more likely to be infected with malaria due to the hormonal changes with more severe symptoms and ... -
Solubility enhancement of selected anti-malarial drugs
(North-West University (South-Africa), 2024-05)Malaria remains a problem experienced globally, with 227 million cases being documented in 2019 by the “World Malaria Report”. Another noted statistic is the occurence of about 54.7 million pregnancies in areas of continuous ...
