Browsing Health Sciences by Subject "Parkinsonisme"
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The synthesis and evaluation of phenoxymethylcaffeine analogues as inhibitors of monoamine oxidase
(North-West University, 2010)Purpose: Monoamine oxidase (MAO) plays a key role in the treatment of Parkinson's disease (PD), since it is the major enzyme responsible for the catabolism of dopamine in the substantia nigra of the brain. Inhibition of ...