Browsing Health Sciences by Subject "Haspin"
Now showing items 1-2 of 2
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Design, synthesis and biological evaluation of selected 7-azaindole derivatives and structurally related compounds as potential inhibitors of disease-related protein kinases
(North-West University (South-Africa), 2021)The bulk of the myriad cellular processes pertaining to normal cellular function in humans are governed by a superfamily of proteins known as protein kinases. Protein kinases account for 1.7% of all human genes and are ... -
Synthesis and biological evaluation of 7-azaindole-based chalcones and related compounds as protein kinase inhibitors
(North-West University (South-Africa), 2021)Protein phosphorylation is a major molecular mechanism through which proteins’ functions are regulated. Protein phosphorylation occurs through protein kinases, and it consists of the transfer of a phosphate group from a ...
