Browsing Health Sciences by Subject "Furosemide"
Now showing items 1-4 of 4
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The effect of filler, active ingredient and Kollidon® VA64 sollubility on the release profile of the active ingredient from wet granulation tablet formulations
(North-West University, 2012)There are mainly two manufacturing processes used in the pharmaceutical industry, namely direct compression and granulation of which granulation can be subdivided into wet granulation and dry granulation. Wet granulation ... -
Effect of the transport medium composition on in vitro drug permeation across excised pig intestinal tissue
(North-West University (South Africa) , Potchefstroom Campus, 2016)A crucial step in the process of drug research and development is the investigation of permeation characteristics of new chemical entities across biological membranes to give an indication of their pharmacokinetic properties. ... -
Improvement of the pharmaceutical availability and membrane permeability of furosemide by formulation design
(North-West University (South-Africa), 2021)Furosemide is a well-known loop diuretic having weak acidic chemical properties. Furosemide belongs to the Biopharmaceutical Classification System (BCS) class IV because it has poor aqueous solubility and poor membrane ... -
Prediction of compressibility of pharmaceutical excipients in solid oral dosage forms
(North-West University (South Africa) , Potchefstroom Campus, 2016)Tablets are one of the most preferred dosage forms for patients, but pre-formulation studies for tablets are often time consuming and expensive. The SeDeM Expert Diagram System attempts to address this problem by decreasing ...