Browsing Health Sciences by Subject "Formulation"
Now showing items 1-10 of 11
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Development of multiple-unit pellet systems by employing the SeDeM expert diagram system
(North-West University (South Africa), 2018)Conventional tablets and capsules are considered the most common and acceptable drug delivery systems, however, in recent years multiple unit pellet systems (MUPS) have become more popular and are considered to be an ... -
Evaluation of the in vitro antimicrobial activity of the Pheroid®-entrapped plant extract of Agapanthus africanus against human pathogens
(North-West University (South-Africa), 2019)Antimicrobial resistance is a major concern as existing antimicrobials are becoming less effective due to misuse and overuse (WHO, 2018b). Identifying novel compounds or treatments with a possible antimicrobial activity ... -
Formulation of 5–Fluorouracil for transdermal delivery
(North-West University, 2010)Non–melanoma skin cancer (NMSC) is the most common human malignancy and it is estimated that over 1.3 million cases are diagnosed each year in the United States (Neville et al., 2007:462). There are three main types of ... -
The formulation of scale items for the best interest of the child
(North-West University (South-Africa), 2020)Although there is a high reported incidence of child sexual abuse cases in South Africa, which in itself is cause for concern, a great concern is what happens to children who have reported abuse to the authorities. To what ... -
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ... -
Formulation, in vitro release and transdermal diffusion of atropine by implementation of the delivery gap principle
(2014)The transdermal delivery route has become a popular alternative to more conventional routes, such as oral administration, but has not yet reached its full potential (Prausnitz & Langer, 2008:1261). Although the transdermal ... -
Formulation, in vitro release and transdermal diffusion of diclofenac salts by implementation of the delivery gap principle
(2013)Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of inflammation and pain (Escribano et al., 2003:203). Diclofenac, a classical NSAID, is considerably more effective as an analgesic, antipyretic ... -
Formulation, in vitro release and transdermal diffusion of Vitamin A and Zinc for the treatment of acne
(North-West University, 2010)Acne vulgaris is the single, most common disease that presents a significant challenge to dermatologists, due to its complexity, prevalence and range of clinical expressions. This condition can be found in 85% of teenage ... -
Formulation, in vitro release and transdermal diffusion of vitamin B3 for treatment of acne
(North-West University, 2009)Acne is an extremely common condition, affecting almost 80% of adolescents and young adults. It is an inflammatory disease, characterised by comedones, papules, pustules and sometimes cysts. Factors causing acne include ... -
Formulation, in-vitro release and transdermal diffusion of alpha-lipoic acid
(North-West University, 2009)Acne is a common disease characterised by follicular hyperkeratinisation, bacterial hipercolonisation as well as immune reactions and inflammation. In acne, reactive oxygen species (ROS) may be released from the damaged ...