Browsing Health Sciences by Subject "Escitalopram"
Now showing items 1-9 of 9
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Chronic effects of pre-adolescent pharmacological and non-pharmacological interventions on depressive-like behaviour in rats
(North-West University, 2018)Similar to adults, major depressive disorder (MDD) also affects children and adolescents, with comparable treatment outcomes. However, only two antidepressants, namely the serotonin reuptake inhibitors fluoxetine and ... -
Cognitive flexibility in the deer mouse and its response to escitalopram and levetiracetam
(North-West University (South-Africa), 2022)Obsessive-compulsive disorder (OCD)1 causes functional impairment which severely and negatively impacts the lives of affected individuals. As its name suggests, OCD is characterised by both obsessions and compulsions. The ... -
Cognitive flexibility in the deer mouse model of obsessive-compulsive disorder and its response to serotonin and adenosine modulation
(North-West University (South-Africa), 2021)Obsessive-compulsive disorder (OCD)1 is a phenotypically heterogeneous psychiatric disorder characterised by repetitive and ritualised behaviours (compulsions), that are purportedly enacted to attenuate the level of distress ... -
A metagenomic microbiome investigation in the deer mouse : a translational approach to obsessive-compulsive disorder
(North-West University (South-Africa), 2019)Obsessive-compulsive disorder (OCD)1 is characterized by persistent, intrusive and often anxiety-provoking thoughts, i.e. obsessions and/or ritualistic behaviors (compulsions) that are expressed in an attempt to reduce the ... -
Nest building and marble burying: Dopaminergic phenotyping of the deer mouse model of obsessive-compulsive disorder (OCD)
(North-West University (South-Africa), 2020)Obsessive-compulsive disorder (OCD1) is a chronic, debilitating psychiatric condition that affects 3% of the global population and is characterized by obsessions, and compulsions. 40 – 60% of patients remain treatment-resistant ... -
Persistent behavioural phenotypes in the deer mouse and its response to serotonergic and dopaminergic intervention
(North-West University (South-Africa), 2019)Obsessive compulsive disorder (OCD)1 is a debilitating psychiatric disorder that presents with intrusive thoughts (obsessions) and repetitive ritualistic behaviour (compulsions) as main symptoms. Selective reuptake inhibitors ... -
A pharmacological and behavioural investigation of anxiety in the deer mouse model of obsessive- compulsive disorder
(North-West University (South-Africa), 2021)Obsessive-compulsive disorder (OCD)1 is a chronic, debilitating psychiatric disorder with a global lifetime prevalence rate of 2.0%-2.9% and which generally manifests in early adulthood. The condition is characterised by ... -
Stereotypical behaviour in the deer mouse (Peromyscus Maniculatus bairdii) : a pharmacological investigation of the frontal–cortico–striatal serotonergic system
(North-West University, 2011)Obsessive–compulsive disorder (OCD) is a psychiatric condition that is characterized by two main symptom cohorts, namely recurrent inappropriate thoughts (obsessions) and seemingly purposeless repetitive motor actions ... -
Tryptophan metabolism in the deer mouse and its response to serotonergic intervention
(North-West University (South-Africa), 2022)Obsessive-compulsive disorder (OCD)1 is a debilitating neuropsychiatric condition that notably infringes on an individual’s quality of life. The condition is characterised by two primary symptoms, namely obsessions (intrusive ...