Browsing Health Sciences by Subject "Cutaneous tuberculosis"
Now showing items 1-7 of 7
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Development of a topical self-emulsifying drug delivery system for optimised delivery
(North-West University (South-Africa), 2020)In order to achieve successful receptor binding affinity at complex pharmacological targets the majority of drugs are of a lipophilic nature. However, optimisation of drug delivery systems for lipophilic drugs presents ... -
Formulation and topical delivery of a safflower oil nano-emulsion containing artemether
(North-West University (South Africa) , Potchefstroom Campus, 2016)Cutaneous tuberculosis (CTB), one of the forms of extra-pulmonary tuberculosis (TB), occurs 1.5% of the time when the Mycobacterium tuberculosis bacterium enters the skin, either through direct contact or through airborne ... -
Formulation and topical delivery of liposomes and proliposomes containing clofazimine
(North-West University (South Africa) , Potchefstroom Campus, 2016)The continual market increase in the transdermal and topical delivery of drugs makes cutaneous drug delivery exploration all the more attractive for scientists (Larraῆeta et al., 2016:62). The key in the delivery of drugs ... -
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ... -
Natural oil nano-emulsion dispersions for the topical delivery of clofazimine, artemisone and decoquinate
(North-West University, Potchefstroom Campus, 2018)Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb) (Godreuil et al., 2007:1), manifests as an extra-pulmonary disease in 3.7 to 8.4% of cases, whereas cutaneous tuberculosis (CTB), which is uncommon, ... -
Self-Double-emulsifying drug delivery Systems: A novel approach to topical fixed-dose anti-tubercular drug delivery
(North-West University (South-Africa), 2023-10)Mycobacteria cause numerous skin infections that are difficult to treat due to intrinsic difficulties of drug permeation into mycobacteria, and their ability to develop resistance to antibiotics. Therefore, the incidence ... -
Transdermal delivery of isoniazid and rifampicin by pheroid technology
(North-West University, 2007)The aim of this in vitro study was to investigate the feasibility of the transdermal delivery of isoniazid (INH) and rifampicin (RMP) by means of the novel PheroidTM technology system. The application of the latter is ...
