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dc.contributor.authorWolmarans, De Wet
dc.contributor.authorScheepers, Isabella M.
dc.contributor.authorHarvey, Brian H.
dc.contributor.authorStein, Dan J.
dc.date.accessioned2018-01-19T12:25:55Z
dc.date.available2018-01-19T12:25:55Z
dc.date.issued2018
dc.identifier.citationWolmarans, D.W. et al. 2018. Peromyscus maniculatus bairdii as a naturalistic mammalian model of obsessive-compulsive disorder: current status and future challenges. Metabolic brain disease, 33(2):443-455. [https://doi.org/10.1007/s11011-017-0161-7]en_US
dc.identifier.issn0885-7490
dc.identifier.issn1573-7365 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/26137
dc.identifier.urihttps://link.springer.com/article/10.1007/s11011-017-0161-7
dc.identifier.urihttps://doi.org/10.1007/s11011-017-0161-7
dc.description.abstractObsessive-compulsive disorder (OCD) is a prevalent and debilitating condition, characterized by intrusive thoughts and repetitive behavior. Animal models of OCD arguably have the potential to contribute to our understanding of the condition. Deer mice (Permomyscus maniculatus bairdii) are characterized by stereotypic behavior which is reminiscent of OCD symptomology, and which may serve as a naturalistic animal model of this disorder. Moreover, a range of deer mouse repetitive behaviors may be representative of different compulsive-like phenotypes. This paper will review work on deer mouse behavior, and evaluate the extent to which this serves as a valid and useful model of OCD. We argue that findings over the past decade indicate that the deer mouse model has face, construct and predictive validityen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.subjectDeer mouseen_US
dc.subjectObsessive-compulsiveen_US
dc.subjectStereotypyen_US
dc.subjectNest buildingen_US
dc.subjectMarble buryingen_US
dc.subjectSocialen_US
dc.subjectAnimal modelen_US
dc.titlePeromyscus maniculatus bairdii as a naturalistic mammalian model of obsessive-compulsive disorder: current status and future challengesen_US
dc.typeArticleen_US
dc.contributor.researchID12324515 - Wolmarans, Petrus De Wet
dc.contributor.researchID11083417 - Harvey, Brian Herbert


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