Show simple item record

dc.contributor.authorVan Rooyen, Yolandi
dc.contributor.authorHuisman, Hugo W.
dc.contributor.authorSchutte, Aletta E.
dc.contributor.authorEloff, Fritz E.
dc.contributor.authorDu Plessis, Johan L.
dc.contributor.authorKruger, Annamarie
dc.contributor.authorVan Rooyen, Johannes M.
dc.identifier.citationVan Rooyen, Y. et al. 2015. South African and international reference values for lung function and its relationship with blood pressure in Africans. Heart, lung and circulation, 24(6):573-582. []en_US
dc.identifier.issn1444–2892 (Online)
dc.description.abstractBackground In South Africa respiratory diseases are highly prevalent, with cardiovascular disease being a manifestation. However, international reference values for lung function are commonly used, which may not be appropriate to correctly identify reduced lung function. An inverse relationship exists between lung function and blood pressure (BP) but is not investigated extensively in black South Africans. Methods We included 2010 Africans from the PURE (Prospective Urban Rural Epidemiology) study (aged > 35 years) in the North West Province. Spirometry was performed and predicted values for forced expiratory volume "in one second (FEV1) and forced vital capacity (FVC) were calculated from South African, European and" United States prediction equations. "Results With the exception of the European predicted values, all other predicted mean FEV1 and FVC were above" "80%. South African reference values displayed the highest percentages of the predicted values for FEV1 and FVC (87.9 and 99.7%, respectively.) BP increased from quintiles five to one for both FEV1 and FVC, (p for trend <0.05)." Conclusions South African reference values yielded higher percentages of predicted FEV1 and FVC values than European and US equations suggesting that South African prediction equations may be more useful when "investigating lung function in black South Africans. Elevated BP is related to reduced lung function, highlighting" the importance in managing both respiratory– and cardiovascular disease.en_US
dc.subjectcardiovascular diseaseen_US
dc.subjectrespiratory diseasesen_US
dc.subjectlung functionen_US
dc.titleSouth African and international reference values for lung function and its relationship with blood pressure in Africansen_US
dc.contributor.researchID10101268 - Du Plessis, Johannes Lodewykus
dc.contributor.researchID10060790 - Eloff, Frederik Christoffel
dc.contributor.researchID10062718 - Huisman, Hugo Willem
dc.contributor.researchID10062416 - Kruger, Annamarie
dc.contributor.researchID10922180 - Schutte, Aletta Elisabeth
dc.contributor.researchID10059539 - Van Rooyen, Johannes Marthinus
dc.contributor.researchID21195706 - Van Rooyen, Yolandi

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record