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dc.contributor.authorBurger, Cornel
dc.contributor.authorShahzad, Yasser
dc.contributor.authorBrümmer, Alicia
dc.contributor.authorGerber, Minja
dc.contributor.authorDu Plessis, Jeanetta
dc.identifier.citationBurger, C. et al. 2016. Traversing the skin barrier through nano-emulsions. Current drug delivery, 14(4):458-472. []en_US
dc.identifier.issn1875-5704 (Online)
dc.description.abstractIn recent years, colloidal delivery systems based on nano-emulsion are gaining popularity; being used for encapsulation and delivery of many drugs. Nano-emulsions are thermokinetically stable dispersion systems, which have been used in topical and transdermal delivery of a number of pharmaceutically active compounds. Nano-emulsions have a narrow droplet size range with tuneable surface properties, which make them an ideal delivery vehicle. Nano-emulsions have a number of advantages over conventional emulsions, including easy preparation using various low and high energy methods, optical transparency, high solubilisation capacity, high stability to droplet aggregation and the ability to penetrate the skin; thus allowing the transdermal delivery of drugs. This review therefore aims at summarising various methods of nano-emulsion formulation and their use as a topical and transdermal delivery vehicle for a number of active pharmaceutical ingredients from different pharmacological classesen_US
dc.publisherBentham Scienceen_US
dc.subjectskin permeationen_US
dc.subjecttopical drug deliveryen_US
dc.subjecttransdermal drug deliveryen_US
dc.titleTraversing the skin barrier with nano-emulsionsen_US
dc.contributor.researchID21661308 - Burger, Cornel
dc.contributor.researchID21205477 - Brümmer, Alicia
dc.contributor.researchID11329025 - Gerber, Minja
dc.contributor.researchID10065318 - Du Plessis, Jeanetta
dc.contributor.researchID26255499 - Shahzad, Yasser

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