Faculty of Health Sciences: Recent submissions
Now showing items 481-500 of 2404
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An HPLC-DAD validated method for the detection and quantification of cortisol, corticosterone and melatonin in plasma samples of two different animal species
(Avoxa, 2019)The monitoring of endogenous hormone plasma levels could be valuable in biomedical, veterinary and pharmaceutical research. A specific high performance liquid chromatography method with diode array detection, for the assay ... -
Waist circumference percentiles of black South African children aged 10 - 14 years from different study sites
(HMPG, 2019)Background. Waist circumference (WC) is a useful predictor of cardiometabolic risk in children. Published data on WC percentiles of children from African countries are limited. Objectives. To describe age- and sex-specific ... -
Fibrinogen and fibrin: an illustrated review
(Wiley, 2019)Since its discovery over 350 years ago, studies of fibrinogen have revealed remarkable characteristics. Its complex structure as a large (340 kDa) hexameric homodimer supports complex roles in hemostasis and homeostasis. ... -
An empowerment narrative leadership program for a disadvantaged community
(Sage, 2019)Purpose: This research is providing social workers with a deeper insight into the process of empowering people from disadvantaged communities with leadership abilities by applying a narrative approach in group work and ... -
Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study
(Elsevier, 2019)Background The associations between the extent of forced expiratory volume in 1 s (FEV1) impairment and mortality, incident cardiovascular disease, and respiratory hospitalisations are unclear, and how these associations ... -
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
(Taylor & Francis, 2019)The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. ... -
Salutogenic versus Pathogenic metaphorical language usage in South Africa's National HIV/AIDS Education Policy
(North-West University, 2019)This study explored the use of metaphorical language in South Africa’s national HIV/AIDS education policy, and to what extent the metaphorical messages conveyed about HIV and AIDS in the policy are essentially health ... -
A review of the pharmacological properties of 3,4-dihydro-2(1h)- quinolinones
(Bentham Science, 2018)The 3,4-dihydro-2(1H)-quinolinone moiety is present in a number of pharmacologically active compounds. These include FDA approved drugs such as cilostazol, carteolol and aripiprazole as well as numerous experimental ... -
NT-proBNP and metabolic risk factors in two ethnic groups: the SABPA cohort study
(Oxford Univ Press, 2018)Background: Natriuretic peptides are vasoactive peptides with several metabolic actions. Purpose: We aimed to explore associations of N-terminal pro-brain natriuretic peptide (NT-proBNP) with metabolic traits in a mixed ... -
A preclinical study of casein glycomacropeptide as a dietary intervention for acute mania
(Oxford Univ Press, 2018)Background Casein glycomacropeptide is a peptide that lacks phenylalanine, tyrosine, and tryptophan. This profile may enable it to deplete phenylalanine, tyrosine, and tryptophan, and subsequently the synthesis of dopamine ... -
Social work and food security: case study on the nutritional capabilities of the landfill waste pickers in South Africa
(Sage, 2018)Food security (or the lack of it) has a direct impact on people’s well-being and is of great concern to many disciplines. The study on which the article is based used Drèze and Sen’s ‘nutritional capability’ concept as a ... -
Challenges and issues in drug utilization research identified from the Latin American and African regions
(Wiley, 2018)Background: Despite advancements in drug utilization research (DUR), these have not been universal. Some regions such as the Latin America (LatAm) and African regions are facing challenges that are impeding the development ... -
Increasing access to drug utilization data globally: developing an action plan
(Wiley, 2018)Background: Drug utilization (DU) research intends to support health authorities in the development of evidence‐informed pharmaceutical policy and practice guidelines, with the interest of the patients and communities in ... -
Pilot of a pharmacoepidemiology capacity building electronic survey for the Latin American and African regions
(Wiley, 2018)Background: The ISPE Global Development Committee in collaboration with the Educational Committee and ISPE Board of Directors aims to build‐up pharmacoepidemiology (PE) research capacity in the Latin America (LatAm) and ... -
Accelerated nutrition transition in the North West Province of South Africa: results from the Prospective Urban and Rural Epidemiology (PURE-NWP-SA) cohort study, 2005 to 2010
(Cambridge Univ Press, 2018)Objective: South Africa (SA) is in the midst of a health transition characterized by a quadruple burden of diseases and a nutrition transition. The existing nutrition transition in SA, accompanied by the coexistence of ... -
The two-year longitudinal relationships between changes in body composition and changes in selected metabolic risk factors (abdominal obesity and blood pressure) among adolescents from Potchefstroom in the North West Province of South Africa
(Wolters Kluwer, 2018)Objectives: To determine the longitudinal relationship between changes in body composition and selected metabolic risk factors (abdominal obesity and BP) among adolescents from the Tlokwe Municipality in the North West ... -
The role of triage to reduce waiting times in primary health care facilities in the North West province of South Africa
(AOSIS, 2018)Background: Worldwide, patients visiting health care facilities in the public health care sector have to wait for attention from health care professionals. In South Africa, the Cape Triage Score system was implemented ... -
Vitamin A supplementation among children aged 6-59 months in 23 sub-Saharan African countries
(Oxford Univ Press, 2018)Background: Vitamin A deficiency is a major contributor to under-five mortality. Improving vitamin A status of children through supplementation increases their resistance to disease and reduces childhood mortality. ... -
Unpacking, summing and anchoring in retrospective time estimation
(Elsevier, 2019)We examined whether or not interventions that have been used to try to influence predictions of future task duration – unpacking, summing and anchoring – had a similar effect on retrospective estimations of duration. In ... -
An in vitro ADME and in vivo pharmacokinetic study of novel TB-active decoquinate derivatives
(Frontiers Media, 2019)Tuberculosis (TB) is currently the leading cause of mortality due to an infectious disease, despite the existence of multiple effective first-line and second-line drugs. The current anti-TB regimen requires a prolonged ...
