Faculty of Health Sciences: Recent submissions
Now showing items 181-200 of 2404
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Growth differentiating factor-15 and its association with traditional cardiovascular risk factors: the African-PREDICT study.
(Elsevier, 2020)Background and aims Growth differentiating factor-15 (GDF-15) is a stress-induced and cardio-protective cytokine, reported to be influenced by a number of cardiovascular risk factors. In older adults, GDF-15 associated ... -
Vascular structure and inflammation in a South African population: the SABPA study
(Karger, 2020)Background and Objective: Inflammation plays a role in the early onset of cardiovascular disease. However, longitudinal studies on this topic, especially in South African populations, are scant. We explored whether early ... -
Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors
(Elsevier, 2020)Protein kinases are important drug targets, especially in the area of oncology. This paper reports the synthesis and biological evaluation of new 7-azaindole derivatives bearing benzocycloalkanone motifs as potential protein ... -
Decolonisation of the Nursing Curriculum by the South African Nursing Students' Association
(UNISA Press, 2019)The South African Nursing Students’ Association (SANSA) held its fourth annual symposium which was co-hosted by the Tshwane University of Technology (TUT) and the University of Pretoria (UP) on 4 to 6 July 2018 -
Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
(Elsevier, 2019)Background Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the ... -
The disconnect between individual-level and population-level HIV prevention benefits of antiretroviral treatment
(Elsevier, 2019)In 2019, the HIV pandemic is growing and soon over 40 million people will be living with HIV. Effective population-based approaches to decrease HIV incidence are as relevant as ever given modest reductions observed over ... -
A comparative analysis on blood pressure in HIV‐infected individuals versus uninfected controls residing in Sub‐Saharan Africa: a narrative review
(Wiley, 2019)Purpose: Elevated blood pressure is a well‐documented risk factor for cardiovascular disease and mortality in Sub‐Saharan Africa (SSA). With SSA also affected by high Human Immunodeficiency Virus (HIV) infection rates, it ... -
São Paulo call to action for the prevention and control of high blood pressure: 2020
(Wiley, 2019)Key Messages About 1/4th of adults have high blood pressure which is the single most important risk for death (including heart disease and stroke). There are effective policies that could facilitate people making healthy ... -
The relationship of blood pressure with uric acid and bilirubin in young lean and overweight/obese men and women: the African-PREDICT study
(Nature, 2020)Mounting evidence supports the central role of oxidative stress and inflammation in obesity and the development of hypertension. However, most studies focusing on the non-enzymatic antioxidants, such as uric acid and ... -
Breast milk and erythrocyte fatty acid composition of lactating women residing in a peri‑urban South African township
(Elsevier, 2020)Data on breast milk fatty acid (FA) composition in South African lactating women in relation to their FA status, as well as on potential compositional changes within feed, are limited. The aim of this study was to assess ... -
Quality of life, physical activity and cardiorespiratory fitness in black African women: B-Healthy project
(Springer, 2020)Purpose To study the associations between physical activity (PA), cardiorespiratory fitness (CRF), and health-related quality of life (HRQoL) in black African women from a low socioeconomic community in South Africa. ... -
Voices of middle childhood children who lost a mother
(Taylor & Francis, 2019)Children’s comprehension of death and how well they cope is fundamentally affected by their stage of development when they are bereaved. This qualitative descriptive research examines the emotions and experiences of children ... -
Interactional therapy: prospects for treating mental health conditions
(Taylor & Francis, 2019)This practice-oriented article proposes Interactional Therapy (IT) for the treatment of mental health conditions. A case example illustrates the IT application and purpose. From this example, IT appears to be of incremental ... -
Regional overview on the double burden of malnutrition and examples of program and policy responses: African region
(Karger, 2019)Sub-Saharan Africa is experiencing the double burden of malnutrition (DBM) with high levels of undernutrition and a growing burden of overweight/obesity and diet-related noncommunicable diseases (NCDs). Undernourishment ... -
Diet and sedentary behaviour in relation to cancer survival. A report from the national health and nutrition examination survey linked to the U.S. mortality registry
(Elsevier, 2020)Background & aims Cancer is the second most common chronic disease and cause of death in the United States. Our aim was to evaluate the associations of sedentary behavior and nutrient intakes with total and cancer-specific ... -
Flinders sensitive line rats are resistant to infarction following transient occlusion of the middle cerebral artery
(Elsevier, 2020)Background Depression is a common complication of stroke and increases the risk of mortality and disability. Pre-stroke depression is a possible risk factor for stroke and has also been linked to adverse outcomes. The ... -
Development and validation of an LC-MS/MS method for the quantification of goserelin in a Pheroid (R) formulation, in simulated intestinal fluid
(Elsevier, 2020)The purpose of this reported study was to develop and validate an LC-MS/MS method for the quantification of goserelin in a Pheroid (R) formulation simulated intestinal fluid. Biopharmaceuticals are formulated in drug ... -
Adjusting haemoglobin values for altitude maximizes combined sensitivity and specificity to detect iron deficiency among women of reproductive age in Johannesburg, South Africa
(MDPI, 2020)In South Africa, haemoglobin (Hb) is measured to screen for iron deficiency (ID). However, low levels of Hb are only a late stage indicator of ID. Furthermore, Hb values are generally not adjusted for altitude even though ... -
Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study
(Elsevier, 2020)Background Global estimates of the effect of common modifiable risk factors on cardiovascular disease and mortality are largely based on data from separate studies, using different methodologies. The Prospective Urban ... -
An analysis of associations between electronic nicotine delivery system users
(AARC, 2020)BACKGROUND: Electronic nicotine-delivery systems have been increasing in prevalence among young adults. Although these devices are marketed to aid in quit smoking, young adults who do not smoke traditional cigarettes are ...
