Show simple item record

dc.contributor.authorDu Plessis, Johan
dc.contributor.authorEloff, Fritz
dc.contributor.authorFranken, Anja
dc.contributor.authorStefaniak, Aleksandr
dc.contributor.authorJohn, Swen
dc.date.accessioned2016-06-10T06:50:27Z
dc.date.available2016-06-10T06:50:27Z
dc.date.issued2013
dc.identifier.citationDu Plessis, J. et al. 2013. International guidelines for the in vivo assessment of skin properties in non-clinical settings. Part 2. Transepidermal water loss and skin hydration. Skin research and technology, 19(3):265-278. [http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-0846]en_US
dc.identifier.issn0909-752X
dc.identifier.issn1600-0846 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/17703
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/srt.12037/abstract
dc.identifier.urihttps://doi.org/10.1111/srt.12037
dc.description.abstractBackground: There is an emerging perspective that it is not sufficient to just assess skin exposure to physical and chemical stressors in workplaces, but that it is also important to assess the condition, i.e. skin barrier function of the exposed skin at the time of exposure. The workplace environment, representing a non-clinical environment, can be highly variable and difficult to control, thereby presenting unique measurement challenges not typically encountered in clinical settings. Methods: An expert working group convened a workshop as part of the 5th International Conference on Occupational and Environmental Exposure of Skin to Chemicals (OEESC) to develop basic guidelines and best practices (based on existing clinical guidelines, published data, and own experiences) for the in vivo measurement of transepidermal water loss (TEWL) and skin hydration in non-clinical settings with specific reference to the workplace as a worst-case scenario. Results: Key elements of these guidelines are: (i) to minimize or recognize, to the extent feasible, the influences of relevant endogenous-, exogenous-, environmental- and measurement/ instrumentation-related factors; (ii) to measure TEWL with a closed-chamber type instrument; (iii) report results as a difference or percent change (rather than absolute values); and (iv) accurately report any notable deviations from this guidelines. Conclusion: It is anticipated that these guidelines will promote consistent data reporting, which will facilitate inter-comparison of study resultsen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectSkin hydrationen_US
dc.subjectskin barrieren_US
dc.subjectstratum corneumen_US
dc.subjecttransepidermal water lossen_US
dc.subjectguidelineen_US
dc.subjectnon-clinicalen_US
dc.titleInternational guidelines for the in vivo assessment of skin properties in non–clinical settings. Part 2. Transepidermal water loss and skin hydrationen_US
dc.typeArticleen_US
dc.contributor.researchID10101268 - Du Plessis, Johannes Lodewykus
dc.contributor.researchID10060790 - Eloff, Frederik Christoffel
dc.contributor.researchID12776998 - Franken, Anja


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record