Vesicular carriers for skin drug delivery: the Pheroid™ technology
Date
2015Author
Kilian, Dewald
Shahzad, Yasser
Fox, Lizelle
Gerber, Minja
Du Plessis, Jeanetta
Metadata
Show full item recordAbstract
The skin remains an attractive area for drug delivery. The skin, however, often limits the ingress of drugs, because of its very low permeability. Much research, focusing on employing a variety of physical and chemical methods, aimed at reversibly altering skin permeability in favour of compounds, has been reported on. Of the many chemical approaches that exist, one comprises the use of vesicular carriers for delivering drugs into and possibly through the skin. This review offers an overview of various vesicles that have been investigated during dermal and transdermal drug delivery research in recent years, with special emphasis on a relatively new carrier, namely the Pheroid™. The progress made to date by our research group with regards to the use of the Pheroid™ as transdermal delivery vector, is also discussed in detail.
URI
http://hdl.handle.net/10394/14762http://www.eurekaselect.com/130760/article
https://doi.org/10.2174/1381612821666150428125812
Collections
- Faculty of Health Sciences [2386]