1-Bromo-2-(10 β-dihydroartemisinoxy)-ethane

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Date
2010Author
Lombard, Marli C.
N'Da, David D.
Breytenbach, Jaco C.
Fernandes, Manuel A.
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The title compound, C17H27BrO5, DEB, is a derivative of artemisinin which is used in malaria therapy. The OR-group at C12 is cis to the CH3-group at C11 and axially oriented on ring D which has a chair conformation. The crystal packing is stabilized by several weak intermolecular C-HO interactions, which combine to form a C-H-O bonded network parallel to (001).
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http://hdl.handle.net/10394/11066http://journals.iucr.org/e/issues/2010/08/00/jj2039/jj2039.pdf
https://doi.org/10.1107/S1600536810029090