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dc.contributor.authorSchutte, Rudolph
dc.contributor.authorSchutte, Aletta E.
dc.contributor.authorHuisman, Hugo W.
dc.contributor.authorVan Rooyen, Johannes M.
dc.contributor.authorFourie, Carla M.T.
dc.date.accessioned2014-06-26T12:28:35Z
dc.date.available2014-06-26T12:28:35Z
dc.date.issued2012
dc.identifier.citationSchutte, A.E. et al. 2012. Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study. International journal of environmental research , 41(4):1114-1123. [http://www.ijer.ir/]en_US
dc.identifier.issn0300-5771
dc.identifier.issn1464-3685
dc.identifier.urihttp://hdl.handle.net/10394/10745
dc.identifier.urihttp://dx.doi.org/10.1093/ije/dys106
dc.identifier.urihttp://ije.oxfordjournals.org/content/41/4/1114.full.pdf+html
dc.description.abstractBackground Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals with optimal blood pressure (BP) (4120/80mm Hg), and their 5-year prediction for the development of hypertension. Methods The Prospective Urban Rural Epidemiology study in the North West Province, South Africa, started in 2005 and included African volunteers (n¼1994; aged430 years) from a sample of 6000 randomly selected households in rural and urban areas. Results At baseline, 48% of the participants were hypertensive (5140/ 90 mmHg). Those with optimal BP (n¼478) were followed at a success rate of 70% for 5 years (213 normotensive, 68 hypertensive, 57 deceased). Africans that became hypertensive smoked more than the normotensive individuals (68.2% vs 49.8%), and they also had a greater waist circumference [ratio of geometric means of 0.94cm (95% CI: 0.86–0.99)] and greater amount of g-glutamyltransferase [0.74 U/l (95% CI: 0.62–0.88)] at baseline. The 5-year change in BP was independently explained by baseline g-glutamyltransferase [R2¼0.23, b¼0.13 U/l (95% CI: 0.01–0.19)]. Alcohol intake also predicted central systolic BP and carotid cross-sectional wall area (CSWA) at follow-up. Waist circumference was another predictor of BP changes [b¼0.18 cm (95% CI: 0.05–0.24)] and CSWA. HIV infection was inversely associated with increased BP. Conclusions During the 5 years, 24% of Africans with optimal BP developed hypertension. The surge in hypertension in Africa is largely explained by modifiable risk factors. Public health strategies should focus aggressively on lifestyle to prevent a catastrophic burden on the national health system.en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.subjectEthnicityen_US
dc.subjectatherosclerosisen_US
dc.subjectalcoholen_US
dc.subjectg-glutamyl transferaseen_US
dc.subjectobesityen_US
dc.titleAre behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective studyen_US
dc.typeArticleen_US
dc.contributor.researchID10922180 - Schutte, Aletta Elisabeth
dc.contributor.researchID12201405 - Schutte, Rudolph
dc.contributor.researchID10062718 - Huisman, Hugo Willem
dc.contributor.researchID10059539 - Van Rooyen, Johannes Marthinus
dc.contributor.researchID10062491 - Fourie, Catharina Maria Theresia


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