dc.contributor.author | Schutte, Rudolph | |
dc.contributor.author | Schutte, Aletta E. | |
dc.contributor.author | Huisman, Hugo W. | |
dc.contributor.author | Van Rooyen, Johannes M. | |
dc.contributor.author | Fourie, Carla M.T. | |
dc.date.accessioned | 2014-06-26T12:28:35Z | |
dc.date.available | 2014-06-26T12:28:35Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Schutte, A.E. et al. 2012. Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study. International journal of environmental research , 41(4):1114-1123. [http://www.ijer.ir/] | en_US |
dc.identifier.issn | 0300-5771 | |
dc.identifier.issn | 1464-3685 | |
dc.identifier.uri | http://hdl.handle.net/10394/10745 | |
dc.identifier.uri | http://dx.doi.org/10.1093/ije/dys106 | |
dc.identifier.uri | http://ije.oxfordjournals.org/content/41/4/1114.full.pdf+html | |
dc.description.abstract | Background Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals with optimal blood pressure (BP) (4120/80mm Hg), and their 5-year prediction for the development of hypertension.
Methods The Prospective Urban Rural Epidemiology study in the North West Province, South Africa, started in 2005 and included African volunteers (n¼1994; aged430 years) from a sample of 6000 randomly selected households in rural and urban areas.
Results At baseline, 48% of the participants were hypertensive (5140/ 90 mmHg). Those with optimal BP (n¼478) were followed at a success rate of 70% for 5 years (213 normotensive, 68 hypertensive, 57 deceased). Africans that became hypertensive smoked more than the normotensive individuals (68.2% vs 49.8%), and they also had a greater waist circumference [ratio of geometric means of 0.94cm (95% CI: 0.86–0.99)] and greater amount of g-glutamyltransferase [0.74 U/l (95% CI: 0.62–0.88)] at baseline. The 5-year change in BP was independently explained by baseline g-glutamyltransferase [R2¼0.23, b¼0.13 U/l (95% CI: 0.01–0.19)]. Alcohol intake also predicted central systolic BP and carotid cross-sectional wall area (CSWA) at follow-up. Waist circumference was another predictor of BP changes [b¼0.18 cm (95% CI: 0.05–0.24)] and CSWA. HIV infection was inversely associated with increased BP.
Conclusions During the 5 years, 24% of Africans with optimal BP developed hypertension. The surge in hypertension in Africa is largely explained by modifiable risk factors. Public health strategies should focus aggressively on lifestyle to prevent a catastrophic burden on the national health system. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Oxford University Press | en_US |
dc.subject | Ethnicity | en_US |
dc.subject | atherosclerosis | en_US |
dc.subject | alcohol | en_US |
dc.subject | g-glutamyl transferase | en_US |
dc.subject | obesity | en_US |
dc.title | Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study | en_US |
dc.type | Article | en_US |
dc.contributor.researchID | 10922180 - Schutte, Aletta Elisabeth | |
dc.contributor.researchID | 12201405 - Schutte, Rudolph | |
dc.contributor.researchID | 10062718 - Huisman, Hugo Willem | |
dc.contributor.researchID | 10059539 - Van Rooyen, Johannes Marthinus | |
dc.contributor.researchID | 10062491 - Fourie, Catharina Maria Theresia | |