Browsing by Subject "Type 2 diabetes"
Now showing items 1-6 of 6
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C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: a longitudinal study
(Elsevier, 2018)Aims To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin. Methods We conducted ... -
Dietary adherence amongst adults with type 2 diabetes mellitus : a South African urban population perspective
(North-West University (South Africa) , Potchefstroom Campus, 2016)Non-communicable diseases are on the increase and expected to be the most common cause of death by the year 2030. Non-communicable diseases and in particular type 2 diabetes mellitus (T2DM) can be managed effectively to ... -
Effects of dieatry onion (Allium cepa L.) in a rodent model of high-fat diet streptozotocin-induced diabetes
(Karger, 2008)Background/Aims: The present study was conducted to investigate the effects of two dietary doses of freeze-dried onion powder on diabetes-related symptoms in a high-fat (HF) diet streptozotocin (STZ)-induced diabetes rat ... -
Evaluation of common genetic variants associated with type 2 diabetes susceptibility in a black South African population
(2014)Introduction: The continual increase of type 2 diabetes (T2D) prevalence is a global public health concern. The aetiology of T2D has not been fully elucidated and this is hampering the development of effective preventative ... -
Exercise increases hyper-acetylation of histones on the Cis-element of NRF-1 binding to the Mef2a promoter: implications on type 2 diabetes
(Elsevier, 2017)Exercise brings changes on the chromatin ensuing the upregulation of many genes that confer protection from type 2 diabetes. In type-2 diabetes, critical genes are down-regulated such as those involved in glucose transport ... -
The phytochemical content and anti-diabetic properties of Aloe ferox and Aloe greatheadii var. davyana
(North-West University, 2009)Motivation: Diabetes mellitus is a non-communicable disease considered to be one of the five leading causes of death worldwide, characterized by hyperglycemia and hyperlipidemia as a result of altered glucose and lipid ...