Browsing by Subject "Tryptophan metabolism"
Now showing items 1-3 of 3
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An exploration into the bio-behavioural characteristics of the Ndufs4 (knockout) mice : a novel preclinical perspective on psychiatric conditions
(North-West University (South-Africa), 2023)The brain and its associated disorders as a field of study are extremely complex, even more so when research strives to create models that mimic human psychiatric conditions. Given that psychiatric illnesses are associated ... -
Social isolation rearing in rats alters plasma tryptophan metabolism and is reversed by sub-chronic clozapine treatment
(Elsevier, 2012)Schizophrenia is associated with increased oxidative stress, although the source of this redox disequilibrium requires further study. Altered tryptophan metabolism has been described in schizophrenia, possibly linked to ... -
Tryptophan metabolism in the deer mouse and its response to serotonergic intervention
(North-West University (South-Africa), 2022)Obsessive-compulsive disorder (OCD)1 is a debilitating neuropsychiatric condition that notably infringes on an individual’s quality of life. The condition is characterised by two primary symptoms, namely obsessions (intrusive ...
