Browsing by Subject "Transposons"

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Molecular and biological characterization of cell-free DNA using an in vitro cell culture model

Bronkhorst, Abel Jacobus (North-West University, Potchefstroom Campus, 2017)

Over the past 40 years, numerous proof-of-principle studies have intermittently demonstrated the translational potential of cfDNA as a non-invasive biomarker for the diagnostication, prognostication and therapy monitoring ...
Sequence analysis of cell-free DNA derived from cultured human bone osteosarcoma (143B) cells

Bronkhorst, Abel Jacobus; Wentzel, Johannes F.; Peters, Dimetrie L.; Aucamp, Janine; Pretorius, Piet J. (Sage, 2018)

The true importance of cell-free DNA in human biology, together with the potential scale of its clinical utility, is tarnished by a lack of understanding of its composition and origin. In investigating the cell-free DNA ...