Browsing by Subject "Transfection"
Now showing items 1-3 of 3
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An analysis of the effect of transformation on global– and gene–specific DNA methylation in four cultured cell lines
(North-West University, 2010)DNA methylation plays a role in several biological functions, such as gene expression regulation, and several endogenous and exogenous factors affect these DNA methylation patterns in the cell. One such alteration of a ... -
Local implementation and optimization of rotavirus reverse genetics systems
(North-West University (South Africa)North-West University, 2020)Reverse genetics (RG) is one of the most powerful tools for the study of viral replication, pathogenesis and for the generation of rationally designed vaccine candidates. The main bottleneck in rotavirus (RV) research has ... -
Preparatory investigations for developing a transcript–based rotavirus reverse genetics system
(North-West University, 2012)Reverse genetics systems that are based on either viral transcripts or cDNA genome segments cloned in plasmids have recently been reported for some of the dsRNA viruses of the Reoviridae family, namely African horsesickness ...
