Browsing by Subject "Transdermal delivery"
Now showing items 1-10 of 16
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A comparative study of lamellar gel phase systems and emzaloids as transdermal drug delivery systems for acyclovir and methotrexate
(North-West University, 2004)The skin forms an attractive and accessible route for systemic delivery of drugs as alternative to other methods of administration, such as the oral and parental methods because of the problems associated with last ... -
Effect of Brij 97 in the presence and absence of carrageenan on the transdermal delivery of 5-Fluorouracil
(North-West University, 2006)The skin is the largest and most easily accessible organ of the human body thus making it the ideal route for systemic drug delivery. The transdermal route of drug delivery offers several advantages compared to the ... -
The effect of emulsifiers and penetration enhancers in emulsions on dermal and transdermal delivery
(North-West University, 2008)Emulsions are widely used as the delivery vehicles of active ingredients. The aim of this project was the investigation of the effect of the emulsifier system on dermal and transdermal delivery. Four different actives with ... -
Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients
(Karger, 2008)In this study the effect of 2 penetration modifiers, dimethyl isosorbide (DMI) and diethylene glycol monoethyl ether (DGME) on the skin delivery of hydroquinone (HQ), salicylic acid (SA) and octadecenedioic acid (DIOIC) ... -
The effects of emulsifiers and emulsion formulation types on dermal and transdermal drug delivery
(Springer, 2015)Emulsions are widely used in the cosmetic and pharmaceutical fields for the topical administration of hydrophilic and lipophilic active ingredients. There exist different types of emulsions, e.g. water-in-oil, oil-in-water, ... -
Formulation of 5–Fluorouracil for transdermal delivery
(North-West University, 2010)Non–melanoma skin cancer (NMSC) is the most common human malignancy and it is estimated that over 1.3 million cases are diagnosed each year in the United States (Neville et al., 2007:462). There are three main types of ... -
Formulation, in vitro release and transdermal diffusion of anti-inflammatory gel preparations containing diclofenac salts
(North-West University, 2010)Most individuals are influenced by pain at some stage in their lives. It can either be of acute or chronic nature. An acute pain condition initiates and is treated within a time span of 12 weeks. Chronic pain can, however, ... -
Formulation, in vitro release and transdermal diffusion of atropine by implementation of the delivery gap principle
(2014)The transdermal delivery route has become a popular alternative to more conventional routes, such as oral administration, but has not yet reached its full potential (Prausnitz & Langer, 2008:1261). Although the transdermal ... -
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ... -
Optimised transdermal delivery of pravastatin
(Elsevier, 2015)Wiechers’ programme “Formulating for Efficacy” initiated a new strategy to optimise the oil phase of topical formulations in order to achieve optimal transdermal drug delivery. This new approach uses the “Delivery Gap ...
