Browsing by Subject "Tight junctions"
Now showing items 1-3 of 3
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Drug absorption enhancement capacities and mechanisms of action of Aloe vera gel materials
(North-West University (South Africa), Potchefstroom Campus, 2018)Oral drug delivery is one of the most preferred and user friendly routes of drug administration. Macromolecular drugs (such as peptides and proteins) generally have a poor bioavailability when administered orally. Absorption ... -
Intestinal drug absorption enhancement by Aloe vera gel and whole leaf extract: in vitro investigations into the mechanisms of action
(MDPI, 2019)The co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the oral bioavailability of these drugs. Absorption-enhancing agents ... -
Permeation enhancement effects of leaf materials from different aloe species on in vitro and ex vivo nasal epithelial models
(2020)Introduction: The nasal route of drug administration offers an alternative way for oral drug delivery and has the benefit of avoiding first-pass metabolism through drug delivery directly into the systemic circulation. The ...