Browsing by Subject "Nuclear magnetic resonance (NMR) spectroscopy"
Now showing items 1-4 of 4
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Metabolomics and biochemical evaluation of skeletal muscle from Ndufs4 knockout mice
(North-West University (South Africa), 2019)The dysfunction of mitochondrial complex I (CI) impedes the most efficient mechanism feeding electrons into the respiratory chain (RC) — a system that, together with ATP synthase (CV), is responsible for the majority of ... -
Miniaturized 1H-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease
(Springer, 2018)Introduction The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics ... -
Miniaturized 1H-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease
(Springer, 2018)Introduction The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics ... -
New statistical approaches for the assessment of metabolomics data
(North-West University, 2018)The aim of this PhD study was primarily to develop statistical methods that can accommodate the characteristics of metabolomics data, as well as assist in answering the underlying biological questions. However, to identify ...
