Browsing by Subject "Nest building"
Now showing items 1-8 of 8
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Anxiety-like behaviour and adenosinergic processes in compulsive-like deer mice (Peromyscus maniculatus bairdii)
(North-West University (South-Africa), 2023)Obsessive-compulsive disorder (OCD)1 is characterized by recurring thoughts (obsessions) and rigid repetition of certain mental or behavioral actions (compulsions) that are often associated with anxiety. In terms of ... -
Associations Between Nesting, Stereotypy, And Working Memory In Deer Mice: Response To Levetiracetam
(Springer, 2023)Background Some deer mice (Peromyscus maniculatus bairdii) exhibit various phenotypes of persistent behaviors. It remains unknown if and how said phenotypes associate with early-life and adult cognitive perturbations, and ... -
An investigation of habitual behaviour in deer mice (Peromyscus maniculatus bairdii) displaying motor persistence
(North-West University (South-Africa), 2023)Obsessive-compulsive disorder (OCD)1 is characterized by thematically specific obsessions, i.e. intrusive thoughts and impulses, and/or compulsions, that is highly repetitive behaviors or mental acts. Obsessions and ... -
Large nest building and high marble-burying: two compulsive-like phenotypes expressed by deer mice (Peromyscus maniculatus bairdii) and their unique response to serotoninergic and dopamine modulating intervention
(Elsevier, 2020)This study aimed to further dissect the deer mouse (Peromyscus maniculatus bairdii) model of compulsive-like behavior with respect to two persistent-like behavioral phenotypes viz. large nest building (LNB) and high ... -
A metagenomic microbiome investigation in the deer mouse : a translational approach to obsessive-compulsive disorder
(North-West University (South-Africa), 2019)Obsessive-compulsive disorder (OCD)1 is characterized by persistent, intrusive and often anxiety-provoking thoughts, i.e. obsessions and/or ritualistic behaviors (compulsions) that are expressed in an attempt to reduce the ... -
Natural compulsive‐like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition
(Wiley, 2020)Obsessive–compulsive disorder (OCD) is a psychiatric illness that significantly impacts affected patients and available treatments yield suboptimal therapeutic response. Recently, the role of the gut–brain axis (GBA) in ... -
Nest building and marble burying: Dopaminergic phenotyping of the deer mouse model of obsessive-compulsive disorder (OCD)
(North-West University (South-Africa), 2020)Obsessive-compulsive disorder (OCD1) is a chronic, debilitating psychiatric condition that affects 3% of the global population and is characterized by obsessions, and compulsions. 40 – 60% of patients remain treatment-resistant ... -
Peromyscus maniculatus bairdii as a naturalistic mammalian model of obsessive-compulsive disorder: current status and future challenges
(Springer, 2018)Obsessive-compulsive disorder (OCD) is a prevalent and debilitating condition, characterized by intrusive thoughts and repetitive behavior. Animal models of OCD arguably have the potential to contribute to our understanding ...