Browsing by Subject "MutPred score"

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Implementing a new variant load model to investigate the role of mtDNA in oxidative stress and inflammation in a bi-ethnic cohort: the SABPA study

Venter, Marianne; Malan, Leoné; Elson, Joanna L.; Van der Westhuizen, Francois H. (Taylor & Francis, 2019)

Mitochondrial DNA (mtDNA) variation has been implicated in several common complex and degenerative diseases, including cardiovascular disease. Inflammation is seen as part of many of these conditions. Mitochondria feature ...