Browsing by Subject "Morris water maze"

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The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats

Hamlyn, Eugene; Brand, Linda; Harvey, Brian Herbert; Shadid, Mohammed (Wolters Kluwer, 2009)

Ampakines have shown beneficial effects on cognition in selected animal models of learning. However, their ability to modify long-term spatial memory tasks has not been studied yet. This would lend credence to their possible ...
Dissociation between learning and memory impairment and other sickness behaviours during simulated Mycoplasma infection in rats

Swanepoel, Tanya; Harvey, Brian Herbert; Harden, Lois M.; Laburn, Helen P.; Mitchell, Duncan (Elsevier, 2011)

To investigate potential consequences for learning and memory, we have simulated the effects of Mycoplasma infection, in rats, by administering fibroblast-stimulating lipopepide-1 (FSL-1), a pyrogenic moiety of Mycoplasma ...
Investigating the role of AMPAkines in an animal model of post-traumatic stress disorder (PTSD)

Hamlyn, Eugene (North-West University, 2008)

Post-traumatic stress disorder (PTSD) is a severe anxiety disorder affecting cognitive function. 1 in 4 individuals exposed to a life-threatening event may develop PTSD, which is characterised by symptoms of hyperarousal, ...