Browsing by Subject "Monkey"

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The effect of Pheroid® technology on the bioavailability of artemisone in primates

Grobler, Lizette (2014)

Malaria is one the world’s most devastating diseases. Several classes of drugs are used to treat malaria. Artemisinin combination therapy is the first line treatment of uncomplicated malaria. The artemisinin derivative, ...
The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone

Grobler, Lizette; Grobler, Anne; Haynes, Richard; Steyn, Hendrik Stefanus; Masimirembwa, Collen; Thelingwani, Roslyn (Taylor & Francis, 2014)

Objectives: The objectives were to determine the pharmacokinetics (PK) of artemisone and artemisone formulated in the Pheroid® drug delivery system in primates and to establish whether the formulation affects the in vitro ...