Browsing by Subject "Metabolomics"
Now showing items 1-10 of 98
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Abalone growth and associated aspects: now from a metabolic perspective
(Wiley, 2018)Worldwide, there are approximately 100 Haliotis species, more commonly known as abalone or ‘Paua’ in New Zealand, ‘Venus's‐ears’ in Greece, ‘Awabi’ in Japan, ‘Perlemoen’ in South Africa and ‘Ormers’ in Europe. Regardless ... -
The altered fatty acylcarnitines, amino acids and organic acids detected in tuberculosis patient urine
(North-West University (South Africa), Potchefstroom Campus, 2018)Mycobacterium tuberculosis is estimated to infect approximately one-third of the world’s population, which can lead to an active, symptomatic disease called tuberculosis (TB), or to asymptomatic states, often referred ... -
The altered human serum metabolome induced by a marathon
(Springer, 2018)Introduction Endurance races have been associated with a substantial amount of adverse effects which could lead to chronic disease and long-term performance impairment. However, little is known about the holistic metabolic ... -
The altered urine metabolome induced by DOTS therapy in pulmonary tuberculosis patients
(North-West University (South Africa), 2023)Metabolomics holds great promise for studying complex diseases like tuberculosis (TB), where treatment outcomes are influenced by a combination of biological, environmental, and social factors. This study aimed to gain a ... -
Application of metabolomics to identify functional metabolic changes associated with Haliotis midae growth
(North-West University, 2018)The South African abalone, "perlemoen" (as it is called locally) industry is largely based on farming with Haliotis midae, which has been commercially cultured in man-made shore-based systems with great success for the ... -
The application of metabolomics toward pulmonary tuberculosis research
(Elsevier, 2019)In the quest to identify novel biomarkers for pulmonary tuberculosis (TB), high-throughput systems biology approaches such as metabolomics has become increasingly widespread. Such biomarkers have not only successfully been ... -
Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test
(Nature, 2019)The mitochondrial energy score (MES) protocol, developed by the Myhill group, is marketed as a diagnostic test for chronic fatigue syndrome/Myalgic Encephalomyelitis (CFS/ME). This study assessed the reliability and ... -
Automated processing of untargeted 1H-NMR metabolomics data of urine from treated TB patients
(North-West University (South Africa), 2022)Metabolomics is becoming an increasingly popular field of study. An analytical platform commonly used for metabolomics studies is proton nuclear magnetic resonance (1H-NMR) spectroscopy. The main challenge of 1H-NMR is ... -
Can a metabolomics-based approach be used as alternative to analyse fatty acid methyl esters from soil microbial communities?
(Elsevier, 2016)Modern high-throughput approaches such as metabolomics, holds promise for investigating microbial communities. This study evaluated the quantitative and qualitative data generation potential of a metabolomics-based approach ... -
Central systolic pressure and a nonessential amino acid metabolomics profile: the African prospective study on the early detection and identification of cardiovascular disease and hypertension
(Wolters Kluwer, 2019)Objectives: Early-life exposures to cardiovascular risk factors may manifest as early vascular ageing, a phenomenon to which black populations are more prone. The metabolome provides insight into the current state and ...
