Browsing by Subject "Mebendazole"

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Characterization of polymorph transformations that decrease the stability of tablets containing the who essential drug mebendazole

Brits, Marius; Liebenberg, Wilna; De Villiers, Melgardt M. (Elsevier, 2010)

This study investigated the influence of moisture and heat on the stability of mebendazole polymorph C in tablets. The polymorphic forms of mebendazole display significant differences in solubility and therapeutic efficacy ...
Variable-temperature X-ray powder diffraction analysis of the crystal transformation of the pharmaceutically preferred polymorph C of mebendazole

De Villiers, Melgardt M.; Terblanche, Rudolf J.; Liebenberg, Wilna; Swanepoel, Erna; Dekker, Theo G. (Elsevier, 2005)

Mebendazole is a common benzimidazole anthelmintic that is water insoluble. It is reported to exist in three different polymorphic forms in the solid state, i.e. polymorph A, B and C. Form C is the pharmaceutically preferred ...