Browsing by Subject "MAO-B inhibitors"

Now showing items 1-3 of 3

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity

Guglielmi, Paolo; Petzer, Anél; Petzer, Jacobus P.; Secci, Danela; Bagetta, Donatella (Taylor & Francis, 2019)

A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic ...
The synthesis and evaluation of benzosuberone derivatives as inhibitors of monoamine oxidase

Bakker, Cornel (North-West University, Potchefstroom Campus, 2018)

Monoamine oxidase (MAO) is responsible for the catabolism of neurotransmitters such as serotonin and dopamine in the central nervous system and peripheral tissues. MAO inhibitors such as selegiline play a vital part in the ...
Synthesis and evaluation of sesamol derivatives as inhibitors of monoamine oxidase

Engelbrecht, Idalet (2014)

Parkinson’s disease is an age-related neurodegenerative disorder. The major symptoms of Parkinson’s disease are closely linked to the pathology of the disease. The main pathology of Parkinson’s disease consists of the ...