Browsing by Subject "MAO-A"
Now showing items 1-4 of 4
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An investigation of indanone derivatives as inhibitors of monoamine oxidase
(North-West University (South Africa), Potchefstroom Campus, 2018)MAO-A and MAO-B are two isoforms of mitochondrial monoamine oxidase (MAO) that are responsible for the deamination of various monoamine substrates. For example tyramine and dopamine are metabolised by both MAO isoforms. ... -
The synthesis and evaluation of benzosuberone derivatives as inhibitors of monoamine oxidase
(North-West University, Potchefstroom Campus, 2018)Monoamine oxidase (MAO) is responsible for the catabolism of neurotransmitters such as serotonin and dopamine in the central nervous system and peripheral tissues. MAO inhibitors such as selegiline play a vital part in the ... -
Synthesis and evaluation of sesamol derivatives as inhibitors of monoamine oxidase
(2014)Parkinson’s disease is an age-related neurodegenerative disorder. The major symptoms of Parkinson’s disease are closely linked to the pathology of the disease. The main pathology of Parkinson’s disease consists of the ... -
The synthesis and evaluation of tetralone derivatives as inhibitors of monoamine oxidase
(North-West University, Potchefstroom Campus, 2018)Monoamienoksidase (MAO)-inhibeerders word gebruik vir die behandeling van toestande wat veroorsaak word deur verlaagde vlakke van neuro-oordragstowwe soos dopamien, noradrenalien en serotonien. MAO-inhibeerders is aanvanklik ...
